中药联合蜂针治疗变应性鼻炎的临床效果

Clinical Effect of Chinese Medicine Combined with Bee Acupuncture in the Treatment of Allergic Rhinitis

目的:探讨中药联合蜂针治疗变应性鼻炎的临床效果。方法:选取2019年12月—2022年12月广州市妇女儿童医疗中心收治的90例变应性鼻炎患儿,随机分为A组(单纯中药治疗)、B组(单纯锋针治疗)、C组(中药联合蜂针治疗),各30例。观察比较三组的炎症因子水平、中医症候积分、免疫球蛋白E(IgE)水平、生活质量评分及临床疗效。结果:治疗后,三组白细胞介素-4(IL-4)均低于治疗前,γ干扰素(INF-γ)高于治疗前,且C组IL-4水平低于A组、B组,INF-γ水平高于A组、B组,差异有统计学意义(P<0.05)。C组临床总有效率为100.00%,高于A组的70.00%、B组的83.33%,差异有统计学意义(P<0.05)。治疗后,三组各项中医症候积分均低于治疗前,且C组流涕、鼻痒鼻塞、喷嚏积分低于A组、B组,差异有统计学意义(P<0.05)。治疗后,三组鼻炎生活质量量表(RQLQ)评分及IgE水平均低于治疗前,且C组均低于A组、B组,差异有统计学意义(P<0.05)。结论:相较于单纯中药或蜂针治疗,变应性鼻炎患者应用中药联合蜂针治疗不仅可以降低患者的炎症因子和IgE水平,同时可以降低其中医症状积分,提高临床疗效和生活质量。

Objective:To explore the clinical effect of Chinese medicine combined with bee acupuncture in the treatment of allergic rhinitis.Method:A total of 90 children with allergic rhinitis treated in Guangzhou Women and Children Medical Center from December 2019 to December 2022 were selected,and they were randomly divided into group A(simple Chinese medicine treatment),group B(simple bee acupuncture treatment)and group C(Chinese medicine combined bee acupuncture treatment),with 30 cases in each group.The levels of inflammatory factors,traditional Chinese medicine syndrome score,immunoglobulin E(IgE)level,quality of life score and clinical efficacy of the three groups were observed and compared.Result:After treatment,the interleukin-4(IL-4)in the three group were lower than those before treatment,and interferon-γ(INF-γ)were higher than those before treatment,and IL-4 level in group C was lower than that in group A and group B,and INF-γlevel was higher than that in group A and group B,the differences were statistically significant(P<0.05).The total clinical effective rate of group C was 100.00%,which was higher than 70.00%of group A and 83.33%of group B,and the difference was statistically significant(P<0.05).After treatment,the scores of various traditional Chinese medicine symptoms in the three groups were lower than those before treatment,and the scores of runny nose,itchy nose and sneezing in group C were lower than those in group A and group B,the differences were statistically significant(P<0.05).After treatment,the score of Rhinoconjunctivitis quality of life questionnaire(RQLQ)and IgE level of all three groups were lower than those before treatment,and group C were lower than those in group A and group B,the differences were statistically significant(P<0.05).Conclusion:Compared with traditional Chinese medicine or bee acupuncture alone,the application of traditional Chinese medicine combined with bee acupuncture in patients with allergic rhinitis can not only reduce the levels of inflammatory factors and IgE,but also reduce the score of traditional Chinese medicine symptoms,and improve the clinical efficacy and quality of life.