超声穴位介导清热化痰汤联合肺泡灌洗对支气管扩张伴感染的影响

The Effect of Ultrasound Acupoint Mediated Qingre Huatan Decoction Combined with Alveolar Lavage on Bronchiectasis with Infection

目的:观察超声穴位介导清热化痰汤联合肺泡灌洗对支气管扩张伴感染的影响。方法:选取2022年8月—2023年9月重庆市巴南区中医院肺病科收治的92例支气管扩张伴感染患者。根据随机数表法将其分为对照组及治疗组,各46例。对照组给予肺泡灌洗,治疗组在对照组基础上给予超声穴位介导清热化痰汤。比较两组临床疗效、中医症候积分、痰液情况、肺部感染情况、相关指标,住院时间及复发率、不良事件及不良反应。结果:治疗组总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后,两组中医症候积分均降低,治疗组中医症候积分低于对照组,差异有统计学意义(P<0.05)。治疗后,两组痰液情况、临床肺部感染评分(CPIS)评分均降低,治疗组痰液情况、CPIS评分均低于对照组,差异有统计学意义(P<0.05)。治疗后,两组白细胞(WBC)、C反应蛋白(CRP)、降钙素原(PCT)、白细胞介素-6均降低,氧合指数升高,治疗组WBC、CRP、PCT、白细胞介素-6均低于对照组,氧合指数高于对照组,差异有统计学意义(P<0.05)。治疗组住院时间短于对照组,复发率低于对照组,差异有统计学意义(P<0.05)。两组不良事件、不良反应发生率比较,差异无统计学意义(P>0.05)。结论:超声穴位介导清热化痰汤联合肺泡灌洗治疗支气管扩张伴感染可提高疗效,安全可靠。

Objective:To observe the effect of ultrasound acupoint mediated Qingre Huatan Decoction combined with alveolar lavage on bronchiectasis with infection.Method:A total of 92 patients with bronchiectasis and infection admitted to the Pulmonary Disease Department of Banan District Traditional Chinese Medicine Hospital in Chongqing from August 2022 to September 2023 were selected.According to the random number table method,they were divided into control group and treatment group,with 46 cases in each group.The control group was given alveolar lavage,while the treatment group was given ultrasound acupoint mediated Qingre Huatan Decoction on the basis of the control group.The clinical efficacy,traditional Chinese medicine symptom scores,sputum situation,pulmonary infection,relevant indicators,hospital stay and recurrence rate,adverse events and reactions were compared between the two groups.Result:The total effective rate of the treatment group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the traditional Chinese medicine syndrome scores of both groups decreased,and the traditional Chinese medicine syndrome score of the treatment group was lower than that of the control group,the differences statistically significant difference(P<0.05).After treatment,the sputum situation and clinical pulmonary infection score(CPIS)score of both groups decreased,the sputum situation and CPIS score of the treatment group were lower than those of the control group,and the differences were statistically significant(P<0.05).After treatment,white blood cell(WBC),C-reactive protein(CRP),procalcitonin(PCT),and interleukin-6 in both groups decreased,while the oxygenation index increased,the WBC,CRP,PCT,and interleukin-6 in the treatment group were lower than those in the control group,and the oxygenation index was higher than that in the control group,the differences statistically significant difference(P<0.05).The hospitalization time of the treatment group was shorter than that of the control group,and the recurrence rate was lower than that of the control group,the differences statistically significant difference(P<0.05).There was no statistically significant difference in the incidence of adverse events and reactions between the two groups(P>0.05).Conclusion:Ultrasound acupoint mediated Qingre Huatan Decoction combined with alveolar lavage can improve the therapeutic effect of bronchiectasis with infection,and is safe and reliable.