海参多糖的提取纯化、化学分析方法和生物活性研究进展

Research progress in extraction,purification,chemical analysis,and biological activity of sea cucumber polysaccharides

海参是我国传统保健食品,具有极高的保健及营养价值。海参多糖是海参的重要活性成分之一,具有免疫调节、抗肿瘤、抗凝血、抗炎、降血糖、降血脂、抗氧化等生物活性,在食品和医疗领域有着巨大的开发价值和应用潜力。海参的品种、多糖的提取和纯化方法的不同,均会使制备的海参多糖在产率、化学组成、化学结构和生物活性等方面存在一定差异。该文综述了近几年国内外关于海参多糖的提取、分离纯化、含量测定、化学组成分析的方法及其生物活性,为海参多糖的深入研究以及开发应用提供理论依据。

Sea cucumber is a traditional health food in China,with high health and nutritional value.Sea cucumber polysaccharide is one of the important active ingredients of sea cucumber.It has biological activities such as immune regulation,anti-tumor,anti-coagulation,anti-inflammatory,hypoglycemic,hypolipidemic,and antioxidant,and has great development value and the application potential in the field of food and medical treatment.Different varieties of sea cucumber,extraction,and purification methods of polysaccharides will lead to certain differences in yield,chemical composition,chemical structure,and biological activity of sea cucumber polysaccharides.The methods of extraction,separation,purification,content determination,chemical composition analysis,and biological activities of sea cucumber polysaccharides at home and abroad in recent years were reviewed,providing a theoretical basis for further research,development,and application of sea cucumber polysaccharides.