经皮肝穿刺胆道引流术后并发胆道感染的影响因素分析

Influencing factors of biliary tract infections after percutaneous transhepatic cholangial drainage

目的探讨经皮肝穿刺胆道引流术(PTCD)后并发胆道感染的影响因素。方法抽取2020年9月至2023年3月于南阳市中心医院行PTCD治疗的患者112例,按术后是否并发胆道感染分为未感染组(90例)与感染组(22例)。收集两组一般资料及临床指标,采用单因素分析、多因素Logistic回归模型对PTCD术后胆道感染的影响因素进行分析。结果单因素分析结果显示,引流方式、术前凝血酶原时间、术前血红蛋白及总胆红素水平是PTCD术后胆道感染的影响因素(P<0.05)。多因素Logistic回归分析结果显示,引流方式、术前血红蛋白水平是PTCD术后胆道感染的独立危险因素(P<0.05)。结论引流方式、术前血红蛋白是PTCD术后胆道感染的独立危险因素,术前预防性使用抗生素对PTCD术后胆道感染发生并无明显影响。

Objective To analyze the influencing factors of biliary tract infections after percutaneous transhepatic cholangial drainage(PTCD).Methods A total of 112 patients who underwent PTCD treatment in Nanyang Central Hospital from September 2020 to March 2023 were selected,and the patients were divided into the non-infected group(90 cases)and the infected group(22 cases)according to whether biliary tract infection after operation.The general information and clinical indicators of the two groups were collected and compared,and univariate analysis and multivariate logistic regression models were used to analyze the influencing factors of biliary tract infection after PTCD.Results The results of univariate analysis showed that drainage method,preoperative prothrombin time,preoperative hemoglobin and level of total bilirubin were influencing factors of biliary tract infection after PTCD(P<0.05).Results of multivariate logistic regression analysis showed that drainage method and preoperative level of hemoglobin were independent risk factors for biliary tract infection after PTCD(P<0.05).Conclusions Drainage method and preoperative hemoglobin are independent risk factors for biliary tract infection after PTCD.Preoperative prophylactic antibiotics have no significant impact on the occurrence of biliary tract infection after PTCD.