脊髓损伤的治疗新进展

Recent progress in the treatment of spinal cord injury

脊髓损伤属于中枢神经系统的重大疾病之一,患者常遗留永久性截瘫及膀胱直肠括约肌功能障碍,终身丧失劳动及生活自理能力,给家庭及社会带来沉重压力和经济负担。近年来,神经干细胞移植治疗、神经外泌体治疗、脑机接口-神经调控治疗、3D打印定制脊髓类器官修复等新技术快速发展,为脊髓损伤患者提供了更有效、更个性化的治疗新策略和新方法。本文针对脊髓损伤的治疗新进展作一述评。

Spinal cord injury is one of the major diseases of central nervous system.The patients suffered from permanent paraplegia and bladder and rectal sphincter dysfunction,and involved with life-long loss of the ability to work and self-care.The family and society were gone through heavy pressure and economic burden.In recent years,new technologies such as neural stem cells transplantation,neuroexosome therapy,brain-computer interface-neural regulation therapy and 3D-printed customized spinal cord organoid repair have been developed rapidly.It will provide more effective and personalized treatment for spinal cord injury patients with new strategies and new methods.This article provides a review of recent progress in the treatment of spinal cord injury.