实时剪切波弹性成像评估慢性乙型肝炎肝纤维化程度的价值

Significance of real-time shear wave elastography in evaluation on degree of liver fibrosis in patients with chronic hepatitis B

目的探讨实时剪切波弹性成像(SWM)评估慢性乙型肝炎(CHB)患者肝纤维化程度的价值。方法观察性研究。抽取2022年8月至2023年8月滨州市中心医院收治的90例CHB肝纤维化患者,纳入对象均经临床综合诊断确诊,且均经SWM检查。将临床综合诊断肝纤维化程度定为标准,评价SWM评估价值。结果90例CHB肝纤维化患者经临床综合诊断证实肝纤维化分期S1期15例,S2期38例,S3期22例,S4期15例。肝脏SWM检查显示,随着肝纤维化分期增加,弹性模量均值随之提高(P<0.05)。SWM检查弹性模量评估肝纤维化程度价值:诊断S2、S3、S4期的曲线下面积分别为0.856、0.868、0.902,有良好的诊断价值。结论CHB患者出现不同程度的肝纤维化程度时肝脏SWM弹性模量值也有明显差异,分期越高弹性模量值也越大,SWE可评估CHB患者肝纤维化程度。

Objective To investigate the significance of real-time shear wave elastography(SWM)in evaluation on degree of hepatic fibrosis in patients with chronic hepatitis B(CHB).Methods This study was a observational trail.A total of 90 patients with CHB liver fibrosis admitted to Binzhou Central Hospital from August 2022 to August 2023 were selected,all of whom were confirmed by clinical comprehensive diagnosis and underwent SWM examination.Taking the clinical comprehensive diagnosis of hepatic fibrosis as the standard,the evaluative value of SWM was assessed.Results Among the 90 patients with CHB liver fibrosis,clinical comprehensive diagnosis confirmed 15 cases at liver fibrosis stage S1,38 cases at stage S2,22 cases at stage S3,and 15 cases at stage S4.The results of liver SWM examination showed that the mean elastic modulus increased with the progress of liver fibrosis stage(P<0.05).In evaluating the degree of liver fibrosis,the area under curve of elastic modulus of liver SWM examination for diagnosing stage S2,S3,and S4 are 0.856,0.868 and 0.902,respectively,indicating good diagnostic value.Conclusions The values of liver SWM elastic modulus are different among CHB patients with different degrees of hepatic fibrosis.As the progress of stage,the elastic modulus value gets higher.The visible SWE cam evaluate degree of liver fibrosis in CHB patients.