分层分区自体脂肪注射术矫正眶下缘凹陷的美学效果研究

Study on the Aesthetic Effect of Stratified and Partitioned Autologous Fat Injection for Correction of Deformities of Inferior Orbital Margin Depression

目的:探究分层分区自体脂肪注射术矫正眶下缘凹陷的美学效果及对眶周色素沉着和细纹的影响。方法:选取2020年6月-2022年6月笔者医院收治的126例眶下缘凹陷患者,随机数字表法将患者分为对照组及观察组,各63例。对照组予以结膜入路眶隔脂肪释放重置术,观察组患者在适量去除眶隔脂肪后予以分层分区结构脂肪、微脂肪颗粒、纳米脂肪注射术。比较两组患者疗效、复发率、泪槽评定量表(Tear trough rating scale,TTRS)评分、疼痛、手术指标、满意度及并发症情况。结果:观察组有效率显著高于对照组,复发率显著低于对照组,差异均具有统计学意义(P<0.05);治疗后两组患者泪沟、色素沉着、颧脂肪垫下垂及皮肤褶皱评分均显著降低(P<0.05),观察组患者泪沟、色素沉着及皮肤褶皱评分显著低于对照组(P<0.05);观察组患者VAS评分、眼部恢复时间、住院时间均显著低(短)于对照组患者,美观度及舒适度评分显著高于对照组患者(P<0.05);两组患者结节、眼部增生及面部神经受损等并发症发生情况比较差异无统计学意义(P>0.05)。结论:分层分区自体脂肪注射术美容效果良好,可显著改善患者眶周色素沉着和皮肤细纹,值得临床推广应用。

Objective To investigate the aesthetic effect of stratified and regional autologous fat injection in correcting infraorbital margin depression,and the impact on periorbital pigmentation and fine lines.Methods A total of 126 patients with infraorbital margin depression who were admitted to the author's hospital from June 2020 to June 2022 were selected,and divided into a control group and an observation group by random number table method,with 63 cases in each group.Patients in the control group(n=63)were treated with orbital fat transfer via conjunctival approach,while patients in the observation group(n=63)were treated with stratified and regional injection of structured fat,micro fat particles and nano fat after appropriate removal of orbital septum fat.The efficacy,recurrence rate,tear trough rating scale(TTRS)score,pain,surgical indicators,satisfaction,and complications were compared between the two groups.Results The effective rate in the observation group was significantly higher than that in the control group,and the recurrence rate was significantly lower than that in the control group(P<0.05).After treatment,the scores for lacrimal sulcus,pigmentation,malar fat pad sagging and skin folds in the two groups were significantly reduced(P<0.05).The scores for lacrimal sulcus,pigmentation and skin folds in the observation group were significantly lower than those in the control group(P<0.05).The VAS score,ocular recovery time and hospital stay of the observation group were significantly lower/shorter than those of the control group.The aesthetic and comfort scores were significantly higher than those of the control group(P<0.05).There was no statistically significant difference in the incidence of complications between the two groups(P>0.05).Conclusion Stratified and regional autologous fat injection can achieve good aesthetic effect in patients with infraorbital margin depression.In addition,it can significantly improve the patients'periorbital pigmentation and fine lines.