面部囊肿型痤疮光动力治疗后瘢痕增生伴慢性创面形成一例

Hypertrophic Scar and Chronic Wound Formaion after Photodynamic Therapy for Facial Cystic Acne:A Case Report

报道1例5-氨基酮戊酸光动力治疗面部痤疮后致局部瘢痕增生伴皮肤慢性创面形成的临床案例。患者为25岁的年轻女性,因面部囊肿型痤疮行5-氨基酮戊酸光动力治疗,治疗结束后患者双侧颊部逐渐出现瘢痕增生伴表皮反复结痂渗液,迁延不愈。患者曾口服异维A酸、外用呋喃西林溶液、甲硝唑乳膏、多磺粘多糖乳膏及脉冲激光等方式治疗,效果均不理想,颊部瘢痕及表皮剥脱、渗液情况无明显好转。给予患者行面部瘢痕分次切除治疗,术后创面愈合良好,未见明显瘢痕增生及渗液等情况出现。光动力治疗面部痤疮后是否会导致治疗区域瘢痕增生、皮肤愈合不佳等长期不良反应值得进一步探究。

A case report on local scar hyperplasia and chronic skin wound formation after 5-aminolevulinic acid photodynamic therapy of facial acne.The patient was a 25 years old young woman who received 5-aminolevulinic acid photodynamic therapy due to facial cystic acne.After treatment,gradually developed scar hyperplasia on both cheeks,accompanied by repeated epidermal scabbing and exudation,which had been long drawn out course.The patient had been treated by taking isotretinoin,topical furacilin solution,metronidazole cream,mucopolysaccharide polysulfate Cream and pulsed laser.There was no significant improvement in the cheek scars,epidermal peeling and exudation.The patient underwent fractional facial scar resection treatment in the author's hospital,and the wound healed well after the surgery,without any obvious scar hyperplasia or exudation.It is worth further exploring whether photodynamic therapy for acne can lead to long-term adverse reactions such as scar hyperplasia and poor skin healing in the treated area.