分析急诊收治的结直肠癌并发急性梗阻的患者接受Ⅰ期根治性切除吻合手术治疗的临床效果及生存率

Clinical Effect and Survival Rate of Patients with Acute Obstruction of Colorectal Cancer Treated by Stage Ⅰ Radical Resection and Anastomosis

目的探讨急诊收治的结直肠癌并发急性梗阻患者行Ⅰ期根治性切除吻合术的效果,以及对生存率的影响。方法回顾性分析2021年1月-2023年1月日照市中心医院治疗的60例结直肠癌并发急性梗阻患者的临床资料,根据治疗方法不同分成基本组(30例,Ⅰ期切除Ⅱ期吻合手术)和研究组(30例,Ⅰ期根治性切除吻合手术)。对比两组患者的手术和住院时间、手术前后血清因子水平、6个月生存率、并发症等情况。结果研究组手术时间和住院时间均短于基本组,血清因子水平低于基本组,差异有统计学意义(P均<0.05);研究组术后并发症发生率(6.67%)低于基本组(26.67%),差异有统计学意义(χ^(2)=4.320,P<0.05);两组术后6个月生存率比较,差异无统计学意义(P>0.05)。结论临床中结直肠癌并发急性梗阻的患者行急诊Ⅰ期根治性切除吻合手术能够有效地减少患者手术与住院的时间,并且改善患者炎性因子的水平,减少术后发生并发症的概率,近期生存率也较高。

Objective To investigate the effect of stage Ⅰ radical resection and anastomosis on the survival rate of patients with acute obstruction of colorectal cancer treated in emergency.Methods A retrospective analysis was con-ducted on the clinical data of sixty patients with acute obstruction of colorectal cancer treated in Rizhao Central Hospital from January 2021 to January 2023.According to different treatment methods,they were divided into basic group(30 cases,stage Ⅰ resection and Stage Ⅱ anastomosis surgery)and study group(30 cases,stage Ⅰ radical resection and anastomosis surgery).The duration of operation and hospital stay,serum factor levels before and after opera-tion,6-month survival rate and complications were compared between the two groups.Results The operation time and hospital stay of the study group were shorter than those of the basic group,and the serum factor level was lower than that of the basic group,and the differences were statistically significant(all P<0.05).The incidence of postoperative complications(6.67%)in the study group was lower than(26.67%)in the basic group,and the difference was statistically significant(χ^(2)=4.320,P<0.05).There was no statistically significant difference in 6-month survival rate be-tween the two groups(P>0.05).Conclusion In clinical patients with acute obstruction of colorectal cancer,emergency stage I radical resection and anastomosis can effectively reduce the length of operation and hospital stay,improve the level of inflammatory factors in patients,reduce the probability of postoperative complications,and have a high short-term survival rate.