探讨参松养心胶囊联合美托洛尔缓释片治疗老年冠心病室性期前收缩的临床疗效

Clinical Effect of Shensong Yangxin Capsule Combined with Metoprolol Sustained-release Tablets in the Treatment of Ventricular Precontraction in Elderly Patients with Coronary Heart Disease

目的探究老年冠状动脉粥样硬化性心脏病(简称冠心病)室性期前收缩采取参松养心胶囊联合美托洛尔缓释片的治疗效果。方法随机选取2021年6月-2023年6月淄博市中医医院收治的100例冠心病室性期前收缩患者为研究对象,按照不同治疗药物分成单一组与联合组,每组50例。单一组的患者采取美托洛尔缓释片进行治疗,联合组的患者采取美托洛尔缓释片联合参松养心胶囊进行治疗。比较两组患者不同用药之后的治疗效果、血压、不良反应等情况。结果联合组患者的治疗总有效率为88.00%,高于单一组的72.00%,差异有统计学意义(χ^(2)=4.000,P<0.05)。治疗后,联合组患者的心率、血压水平、室性期前收缩次数低于单一组,差异有统计学意义(P均<0.05)。两组不良反应比较,差异无统计学意义(P>0.05)。结论采取参松养心胶囊联合美托洛尔缓释片能够有效地提高患者的治疗效果,改善患者的心率以及血压水平,降低室性期前收缩次数,且联合用药方式安全性较高。

Objective To explore the therapeutic effect of Shensong Yangxin capsule combined with metoprolol sustained-release tablets in the treatment of ventricular precontraction in elderly patients with coronary atheroscle-rotic heart disease(coronary heart disease).Methods A total of 100 patients with ventricular premature contraction of coronary heart disease admitted to Zibo Hospital of Traditional Chinese Medicine from June 2021 to June 2023 were randomly selected as the research objects.According to different treatment drugs,they were divided into single group and combined group,with 50 cases in each group.Patients in the single group were treated with metoprolol sustained-release tablets,and patients in the combined group were treated with metoprolol sustained-release tablets combined with Shensong Yangxin capsules.The therapeutic effects,blood pressure and adverse reactions of the two groups were compared after different medications.Results The total effective rate of the combined group of patients was 88.00%,which was higher than the 72.00%of the single group,and the difference was statistically significant(χ^(2)=4.000,P<0.05).After treatment,the heart rate,blood pressure levels,and the number of ventricular premature contractions were lower in the combination group than in the single group,and the differences were statistically significant(all P<0.05).There was no statistically significant difference in adverse reactions between the two groups(P>0.05).Conclusion Shensong Yangxin capsule combined with metoprolol sustained-release tablets can effectively improve the therapeutic effect of patients,improve the heart rate and blood pressure level of patients,reduce the number of ventricular prema-ture contractions,and the safety of combined medication is high.