益肾通淋排石汤联合体外震波碎石术治疗泌尿系统结石的临床疗效研究

Clinical Efficacy Study of Yishen Tonglin Paishi Decoction Combined with Extracorporeal Shock Wave Lithotripsy in the Treatment of Urinary System Stones

目的研究益肾通淋排石汤与体外震波碎石术在泌尿系统结石治疗中的作用。方法回顾性选取2022年5月-2023年4月泰州市第四人民医院收治的80例泌尿系统结石患者的临床资料,根据治疗方法不同分为对照组(n=40)、研究组(n=40)。两组均行体外震波碎石术,对照组术后口服阿莫西林胶囊,研究组术后服用益肾通淋排石汤。对比两组排石效果,治疗前及治疗后8 d,检测两组血清降钙素原(Procalcitonin,PCT)及C-反应蛋白(C-Reactive Protein,CRP)水平,统计两组并发症发生率,对比生活质量。结果研究组结石排尽率(97.50%)高于对照组(85.00%),差异有统计学意义(χ^(2)=3.914,P=0.048);研究组排石时间(4.92±0.37)d短于对照组(5.27±0.64)d,差异有统计学意义(t=2.994,P=0.004);治疗后8 d,研究组PCT及CRP水平均低于对照组,差异有统计学意义(P均<0.05);研究组并发症总发生率低于对照组,生活质量高于对照组,差异有统计学意义(P均<0.05)。结论在泌尿系统结石的治疗中,将益肾通淋排石汤应用于体外震波碎石术后,能够提高排石效果,缓解机体炎症,且有助于降低并发症发生风险,从而提高患者生活质量。

Objective To study the role of Yishen Tonglin Paishi decoction and extracorporeal shock wave lithotripsy in the treatment of urinary stones.Methods Clinical data of 80 patients with urinary calculi admitted to Taizhou Fourth People's Hospital from May 2022 to April 2023 were retrospectively selected,and they were divided into control group(n=40)and study group(n=40)according to different treatment methods.Both groups underwent extracorporeal shock wave lithotripsy,the control group took amoxicillin capsules after operation,and the study group took Yish-entonglin Paishi decoction after operation.The effect of stone removal was compared between the two groups.The levels of procalcitonin(PCT)and C-reactive protein(CRP)in serum of the two groups were detected before treatment and 8 days after treatment.The incidence of complications in the two groups was analyzed and the quality of life was compared.Results The stone expulsion rate of the study group(97.50%)was higher than that of the control group(85.00%),and the difference was statistically significant(χ^(2)=3.914,P=0.048).The stone removal time of the study group(4.92±0.37)d was shorter than that of the control group(5.27±0.64)d,and the difference was statistically sig-nificant(t=2.994,P=0.004).At 8 days after treatment,PCT and CRP levels in the study group were lower than those in the control group,and the differences were statistically significant(both P<0.05).The complication rate of the study group was lower than that of the control group,and the quality of life of the control group was higher,and the differences were statistically significant(both P<0.05).Conclusion In the treatment of urinary stones,applying Yishen Tonglin Paishi decoction to extracorporeal shock wave lithotripsy can improve the effect of stone removal,relieve the inflammation of the body,and help to reduce the risk of complications,thereby improving the quality of life of patients.