三种根管充填方法治疗慢性牙髓炎和根尖周炎的效果及对GI、SBI、PD及IL-1β水平的影响

Effects of three root canal filling methods on chronic pulpitis and periapical periodontitis and its influences on GI,SBI,PD and IL-1βlevel

目的 比较三种根管充填方法对慢性牙髓炎和根尖周炎患者牙龈指数(GI)、龈沟出血指数(SBI)、牙周袋深度(PD)以及白细胞介素-1β(IL-1β)水平的影响。方法 将2020年10月至2021年12月我院接收的120例慢性牙髓炎和根尖周炎患者作为研究对象,根据随机数字表法将其分为A、B、C组,各40例。A组选择冷牙胶侧方加压根管充填治疗,B组选择热牙胶根管充填治疗,C组选择单尖法根管充填治疗。比较三组的GI、SBI、PD以及IL-1β水平,并评估根管充填时间、充填质量。结果 治疗后,三组的GI、SBI、PD及IL-1β水平均显著降低,差异具有统计学意义(P<0.05);治疗后,B组、C组的GI、SBI、PD以及IL-1β水平均低于A组,差异具有统计学意义(P<0.05);治疗后,B组和C组的GI、SBI、PD以及IL-1β水平比较,差异无统计学意义(P>0.05)。A组的每个根管充填时间为(156.93±9.53)s,B组为(83.70±6.33)s,C组为(57.30±5.25)s,三组间比较,差异具有统计学意义(P<0.05)。三组的根管充填质量合格率比较,差异无统计学意义(P>0.05)。结论 将热牙胶根管充填与单尖法根管充填应用到牙髓炎和根尖周炎的治疗中,可有效降低患者的GI、SBI、PD以及IL-1β水平,且减少椅旁操作时间,具有较高的临床应用价值,值得推广。

Objective To compare the influences of three root canal filling methods on gingival index(GI),sulcus bleeding index(SBI),pocket depth(PD)and interleukin-1β(IL-1β)level in patients with chronic pulpitis and periapical periodontitis.Methods From October 2020 to December 2021,120 patients with chronic pulpitis and periapical periodontitis admitted to our hospital were selected as the research objects.According to the random number table method,the patients were divided into group A,B and C,with 40 cases in each group.The group A was treated with cold gutta-percha lateral compression root canal filling,the group B was treated with hot gutta-percha root canal filling,and the group C was treated with single tip root canal filling.The GI,SBI,PD and IL-1βlevel of the three groups were compared,and the root canal filling time and filling quality were evaluated.Results After treatment,the GI,SBI,PD and IL-1βlevel of the three groups significantly decreased,and the differences were statistically significant(P<0.05);after treatment,the GI,SBI,PD and IL-1βlevel in the group B and the group C were lower than those in the group A,and the differences were statistically significant(P<0.05);after treatment,there were no significant differences in GI,SBI,PD and IL-1βlevel between the group B and the group C(P>0.05).Each root canal filling time of the group A was(156.93±9.53)s,the group B was(83.70±6.33)s,the group C was(57.30±5.25)s,and the differences between the three groups were statistically significant(P<0.05).There was no significant difference in the pass rate of root canal filling quality among the three groups(P>0.05).Conclusion The hot gutta-percha root canal filling and single tip root canal filling applied in the treatment of pulpitis and periapical periodontitis can effectively decrease the GI,SBI,PD and IL-1βlevel of patients,reduce the chairside operation time,and has high clinical application value,which is worthy of promotion.