肌骨超声联合CT能谱成像在不同临床时期痛风患者诊断中的敏感度和准确性分析

Sensitivity and Accuracy Analysis of Muscle Bone Ultrasound Combined with CT Energy Spectrum Imaging in Different Clinical Stages of Gout Patients

目的:研究肌骨超声联合CT能谱成像在痛风患者不同临床时期的应用价值。方法:回顾性分析2021年1月—2023年6月在广州医科大学附属惠州医院超声科进行肌骨超声检查、CT能谱检查的66例疑似痛风患者的临床资料。以关节穿刺和镜检尿酸单钠晶体为诊断“金标准”,对比单一肌骨超声、CT能谱成像诊断和二者联合诊断对痛风的诊断效能(敏感度、准确性)及对痛风不同临床时期的诊断符合率(急性期、间歇发作期、慢性关节炎期)。结果:肌骨超声联合CT能谱成像的诊断敏感度(100%)、准确性(96.97%)均高于单一肌骨超声(85.96%、77.27%)、CT能谱成像(89.47%、81.82%)(P<0.05)。肌骨超声联合CT能谱成像对急性期、间歇发作期、慢性关节炎期的诊断符合率均高于单一肌骨超声、CT能谱成像(P<0.05)。结论:在痛风患者中采用肌骨超声联合CT能谱成像诊断,能提高诊断敏感度、准确性,并明确患者的临床时期,在临床治疗中具有重要指导价值。

Objective:To study the application value of muscle bone ultrasound combined with CT energy spectrum imaging in different clinical stages of gout patients.Method:A retrospective analysis was conducted on the clinical data of 66 patients with suspected gout who underwent muscle bone ultrasound and CT energy spectrum examination in Huizhou Hospital Affiliated to Guangzhou Medical University from January 2021 to June 2023.Joint puncture and microscopic examination of monosodium urate crystals were used as the diagnostic"gold standard",The diagnostic efficacy(sensitivity,accuracy)of and single muscle bone ultrasound,CT energy spectrum imaging diagnosis and the combination of the two for gout were compared,as well as the diagnostic coincidence rate for gout at different clinical stages(acute stage,intermittent attack stage,chronic arthritis stage),while the muscle bone ultrasound and CT energy spectrum imaging characteristics of gout patients at different clinical stages were analyzed.Result:The diagnostic sensitivity(100%)and accuracy(96.97%)of muscle bone ultrasound combined with CT energy spectrum imaging were higher than those of single muscle bone ultrasound(85.96%,77.27%)and CT energy spectrum imaging(89.47%,81.82%)(P<0.05).The diagnostic accuracy of muscle bone ultrasound combined with CT energy spectrum imaging in acute stage,intermittent attack stage,and chronic arthritis stages was higher than those of single muscle bone ultrasound and CT energy spectrum imaging(P<0.05).Conclusion:The use of muscle bone ultrasound combined with CT energy spectrum imaging in gout patients can improve diagnostic sensitivity and accuracy,and accurately determine the clinical period of the patient.It has important guiding value in clinical treatment.