基于文献计量学的生物医药产业研究热点分析

Analysis of Research Hotspots in Biomedical Industry Based on Bibliometrics

目的对生物医药产业的中英文文献进行计量学分析,探究其研究热点和发展趋势。方法基于中国国家知识基础设施(CNKI)与Web of Science(WOS)数据库,检索2002—2022年生物医药产业相关文献,通过Excel、CiteSpace软件对发文量、发文作者、发文机构、国家/地区、发文期刊、关键词、文献共被引进行可视化分析,探讨生物医药产业的研究概况与未来发展趋势。结果CNKI检索文献1853篇,WOS检索文献685篇,共2538篇。中英文发文总量最高为2018年140篇;收录生物医药产业相关文章最多的中英文期刊分别是《中国新药杂志》与《DRUG DISCOVERY TODAY》;关键词分析显示研究热点主要在产业集群、技术创新等方面;被引用频次最高的文献主要研究内容为产业政策与技术研发。结论生物医药产业研究的年发文量呈现增长趋势,研究角度及方向多样。推测生物医药产业未来研究热点将主要围绕生物医药产业技术创新、发展战略、人才培养、概念框架与人工智能等方面。

Objective To conduct a bibliometric analysis of Chinese and English literature on the biopharmaceutical industry,and to explore its research hotspots and development trends.Methods Based on the China National Knowledge Infrastructure(CNKI)and Web of Science(WOS)databases,relevant literature on the biopharmaceutical industry from 2002 to 2022 was searched.Visual analysis of publication volume,author,institution,country/region,journal,keywords,and co-citation of literature was conducted using Excel and CiteSpace software.Based on the visualization results,the research overview and future development trends of the biopharmaceutical industry were explored.Results The search result of CNKI and WOS were 1853 and 685 articles,totaling 2538.The highest number of articles published in Chinese and English was 140 in 2018.The Chinese and English journals that contained the most articles related to the biopharmaceutical industry were"Chinese Journal of New Drugs"and"DRUG DISCOVERY TODAY",respectively.Keyword analysis showed that research hotspots mainly focus on industrial clusters,and technological innovation.The most frequently cited literature mainly focuses on industrial policy,and technological research and development.Conclusions The annual publication volume of research in the biopharmaceutical industry is increasing,and research perspectives and directions are also more diverse.It is speculated that the future research hotspots of the biopharmaceutical industry will mainly focus on technological innovation,development strategies,talent cultivation,conceptual frameworks,and artificial intelligence.