补气化瘀方联合低频脉冲电刺激治疗子宫复旧不全气虚血瘀证患者的效果

Effects of Buqi Huayu decoction combined with low-frequency pulse electrical stimulation in treatment of patients with incomplete uterine involution and qi deficiency and blood stasis syndrome

目的:观察补气化瘀方联合低频脉冲电刺激治疗子宫复旧不全气虚血瘀证患者的效果。方法:选取2021年3月至2023年3月该院收治的86例子宫复旧不全气虚血瘀证患者进行前瞻性性研究,按照随机数字表法将其分为对照组和观察组各43例。对照组采用低频脉冲电刺激治疗,观察组在对照组基础上联合补气化瘀方治疗,两组均连续治疗7 d。比较两组临床疗效,治疗前后中医证候积分、症状相关指标(恶露结束时间、腰腹坠胀消失时间、子宫压痛消失时间)水平、子宫动脉血流参数[搏动指数(PI)、阻力指数(RI)、收缩期峰值流速(PSV)]水平,以及不良反应发生率。结果:观察组治疗总有效率为90.70%(39/43),高于对照组的69.77%(30/43),差异有统计学意义(P<0.05);治疗后,观察组主症、次症等中医证候积分均低于对照组,差异有统计学意义(P<0.05);观察组恶露结束时间、子宫压痛消失时间、腰腹坠胀消失时间均短于对照组,差异有统计学意义(P<0.05);治疗后,观察组RI、PI水平均低于对照组,PSV水平高于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:补气化瘀方联合低频脉冲电刺激治疗子宫复旧不全气虚血瘀证患者可提高治疗总有效率,降低中医证候积分,改善症状相关指标和子宫动脉血流参数水平,效果优于单纯低频脉冲电刺激治疗。

Objective:To observe effects of Buqi Huayu decoction combined with low-frequency pulse electrical stimulation in treatment of patients with incomplete uterine involution and qi deficiency and blood stasis syndrome.Methods:A prospective study was conducted on 86 patients with incomplete uterine involution and qi deficiency and blood stasis syndrome admitted to this hospital from March 2021 to March 2023.According to the random number table method,they were divided into control group and observation group,43 cases in each group.The control group was treated with low-frequency pulse electrical stimulation,while the observation group was treated with Buqi Huayu decoction on the basis of that of the control group.Both groups were treated for 7 d.The clinical efficacy,the TCM syndrome scores,the symptom-related indicators(lochia end time,waist and abdomen bulge disappearance time,uterine tenderness disappearance time)levels,the uterine artery blood flow parameters[pulsatility index(PI),resistance index(RI),peak systolic velocity(PSV)]levels,and incidence of adverse reactions were compared between the two groups before and after the treatment.Results:The total effective rate of the observation group was 90.70%(39/43),which was higher than 69.77%(30/43)of the control group,and the difference was statistically significant(P<0.05).After the treatment,the scores of TCM syndromes such as main symptoms and secondary symptoms in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The lochia end time,the waist and abdomen bulge disappearance time,the uterine tenderness disappearance time in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After the treatment,the RI and PI levels in the observation group were lower than those in the control group,the PSV level was higher than that in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusions:Buqi Huayu decoction combined with low-frequency pulse electrical stimulation can improve the total effective rate of treatment,reduce the TCM syndrome scores,improve the levels of symptoms related indicators and uterine artery blood flow parameters in the treatment of the patients with incomplete uterine involution and qi deficiency and blood stasis syndrome.Moreover,it is superior to single low-frequency pulse electrical stimulation treatment.