卵巢功能异常与妊娠结局相关性及其机制概述

Correlation between abnormal ovarian function and pregnancy outcomes and its mechanism

卵巢功能异常主要包括卵巢功能低下和高反应,是女性不孕不育的重要原因之一。卵巢功能异常女性妊娠结局不良可表现为流产率升高、活产率下降,以及妊娠并发症和新生儿风险增加,其原因与卵子质量下降和母体内环境紊乱等因素有关。本文对卵巢功能异常对妊娠结局的影响及其机制进行综述,以期为临床综合诊疗和相关研究提供参考。

Abnormal ovarian function,including ovarian dysfunction and high ovarian response,is one of the important causes of female infertility.Women with abnormal ovarian function have undesirable pregnancy outcomes,manifested as high miscarriage rate,low live birth rate,increased pregnancy complications,and neonatal risk.The unsatisfactory pregnancy outcomes caused by abnormal ovarian function are attributed to the decline of oocyte quality and the disruption of the maternal environment.This article reviews the impact of abnormal ovarian function on pregnancy outcomes and its mechanism,so as to provide reference for the clinical comprehensive diagnosis and treatment and relative research.