中医治疗三阴性乳腺癌的研究进展

Research progress of Chinese medicine in the treatment of triple-negative breast cancer

三阴性乳腺癌(TNBC)是乳腺癌中恶性度最高的分型,具有肿瘤体积较大、高组织学分级、高侵袭性、高死亡率等特点。近年来,中医药在抑制TNBC细胞的增殖和转移、逆转化疗耐药、调节免疫、增强疗效、减轻辅助治疗不良反应等方面发挥出重要作用。本文从TNBC的中医认识、病因病机、辨证论治、中医内治、中医外治等方面展开综述,以期为TNBC的中医药治疗提供参考。

Triple-negative breast cancer(TNBC)is the most malignant subtype of breast cancer,which is characterized by large tumor size,high histological grading,high invasiveness and high mortality.In recent years,traditional Chinese medicine(TCM)has played an important role in inhibiting the proliferation and metastasis of TNBC cells,reversing chemotherapy resistance,regulating immunity,enhancing efficacy,and alleviating the adverse effects of adjuvant therapy.This article reviews the TCM understanding of TNBC,etiology and pathogenesis,identification and treatment,TCM internal treatment,and TCM external treatment,with a view to providing reference for TCM treatment of TNBC.