基于增强现实技术的八段锦训练对老年高血压患者认知功能的影响

Effect of augmented reality-assisted baduanjin on cognitive functions in elderly patients with hypertension

目的 观察基于增强现实技术(augmented reality, AR)的八段锦训练对老年高血压合并轻度认知障碍(mild cognitive impairment, MCI)患者认知功能、记忆力、日常生活能力、血压水平及血清胱抑素C(cystatin-C,Cys-C)、脑源性神经营养因子(brain-derived neurotrophic factor, BDNF)水平的影响。方法 选取老年高血压合并MCI患者150例,按随机数字表法分为AR八段锦组、常规八段锦组、对照组各50例。对照组进行常规健康宣教与治疗,常规八段锦组在对照组基础上进行由康复师组织监督完成的八段锦训练,每周运动3次,每次60 min,共持续24周。AR八段锦组在对照组的基础上,接受基于AR技术的体感互动八段锦训练,运动处方同常规八段锦组。于干预前后分别对3组患者应用蒙特利尔认知评估量表(Montreal cognitive Assessment, MoCA)、简易智能量表(mini-mental state examination, MMSE)评分进行认知功能评定,应用中国修订韦式记忆量表(Wechsler memory scale, WMS-RC)评估患者瞬时、短时、长时记忆,日常生活活动能力(activities of daily living, ADL)评分评估患者生活质量,测量血压水平及测定Cys-C、BDNF水平。结果 干预后,接受八段锦训练的2组患者MoCA评分、MMSE评分、ADL评分、瞬时记忆评分、Cys-C和BDNF水平、收缩压及舒张压较组内干预前均有显著改善(P<0.05),且干预后的上述指标均优于对照组,差异均有统计学意义(P<0.05)。2组接受八段锦锻炼的患者,治疗后MoCA评分、MMSE评分、ADL评分、瞬时记忆评分、Cys-C和BDNF水平、收缩压及舒张压比较,AR八段锦组优于常规八段锦组,且治疗依从性高,差异均有统计学意义(P<0.05)。结论 基于增强现实技术的八段锦训练可有效地改善老年高血压合并轻度认知障碍患者的认知功能和血压水平,提高其生命质量。

Objective To explore the effect of augmented reality(AR)-assisted baduanjin exercise on cognition,memory,life quality,blood pressure,the serum level of Cystatin-C(Cys-C)and brain-derived neurotrophic factor(BNDF)in elderly hypertensive patients with mild cognitive impairment(MCI).Methods A total of 150 elderly hypertensive patients with MCI were selected as the subjects.They were randomly divided into three groups:control group,conventional baduanjin group,and ARassisted baduanjin group,each consisting of 50 participants.The control group received routine health education and treatment,the conventional baduanjin group underwent supervised baduanjin exercise organized by rehabilitation therapists on top of the control group's intervention,and the AR-assisted baduanjin group,in addition to the control group's intervention,received AR-assisted baduanjin exercise guided by AR technology.The exercise sessions occurred three times a week for a duration of 60 minutes each,spanning 24 weeks.All 3 groups were assessed using the Montreal Cognitive Assessment(MoCA)scale and Mini-mental State Examination(MMSE)scale.The Wechsler Adult Memory Scale(including instantaneous memory,short-term memory and long-term memory)were applied to assess the memory of the subjects.Activity of Daily Living Scale(ADL)was employed to assess their quality of life.Blood pressure,the level of Cys-C and BNDF were also administered before and after the 24-week intervention.Results After intervention,the MoCA score,MMSE score,ADL score,instantaneous memory score,Cys-C and BDNF levels,systolic and diastolic blood pressure in both baduanjin groups were significantly improved compared to before intervention(P<0.05),and the above indicators were better than the control group after intervention,with statistically significant differences(P<0.05).After treatment,the MoCA score,MMSE score,ADL score,instantaneous memory score,Cys-C and BDNF levels,systolic and diastolic blood pressure were compared between the two baduanjin groups.The ARassisted baduanjin group exhibited superior outcomes compared to the conventional baduanjin group,and the treatment compliance was high,with statistical significance(P<0.05).Conclusion AR-assisted baduanjin can effectively improve the cognition and lower blood pressure levels of elderly hypertensive patients with mild cognitive impairment,as well as improving their quality of life.