基于络病理论探讨胰腺癌炎癌转化的防治

Discussion on tthe prevention1 and treatment of inflammation-tumor transformation of pancreatic cancer based on the collateral disease theory

胰腺癌又称“癌中之王”,其起病隐匿,难以早期诊断,发展迅速,预后极差。络病学主要研究络病的发病特点、病机变化、辨证论治等内容,络病理论体系从《黄帝内经》首次论述络脉及络病,到现代医家的深入研究,形成了基于络病学对肿瘤的认知。探索炎癌转化的关键节点,及早干预,是实现胰腺癌早防、早治的重要手段。胰络是胰腺癌炎癌转化关键病位,伏阳是胰腺癌炎癌转化关键病机。胰腺癌炎癌转化是“气病—血病—毒生”的三阶段病理变化。基于络病理论防治胰腺癌炎癌转化,主要包括扶正通络、理气通络、化痰通络、逐瘀通络、解毒通络和解郁通络等治法。

Pancreatic cancer,recognized as the king of carcinoma,is characterized by a concealed onset,challenging early diagnosis,rapid development,and a poor prognosis.Collateral disease theory,focusing on the onset characteristics,pathogenic changes,and syndrome differentiation-based diagnosis and treatment,has evolved from Huangdi Nejing to modern in-depth research,providing a foundation for understanding tumors.The key to achieving early prevention and treatment of pancreatic cancer lies in exploring the crucial nodes of inflammation-tumor transformation and implementing timely interventions.The pancreatic collateral plays a pivotal role in the inflammation-tumor transformation of pancreatic cancer,with latent yang evils being a key pathogenic factor.This transformation encompasses three stages of pathological changes:qi disease-blood disease-toxin generation.In the context of collateral disease theory,the prevention and treatment method for inflammation-tumor transformation of pancreatic cancer involve strengthening the body to dredge the collaterals,promoting qi to dredge the collaterals,resolving phlegm to dredge the collaterals,removing blood stasis to dredge the collaterals,clearing toxins to dredge the collaterals,and relieving depression while dredging the collaterals.