肺癌气道播散的影像学研究进展

Research Progress on Radiology in Spread Through Air Space in Lung Cancer

肺癌气道播散(STAS)是指肿瘤细胞以微乳头状细胞团、实性细胞巢或单个细胞等形式存在于主瘤体之外的气道中。随着肺癌研究的不断深入,预测肺癌STAS在诊治和预后中有重要的价值,因此在2015年世界卫生组织将其确定为肺腺癌的一种新的侵袭方式。近年来,利用影像学方法预测STAS的有无已经成为研究的热点。目前相关研究的结果已证实了影像学预测STAS的可行性,进一步深入的研究对发现更加可靠和准确的影像学预测方法十分必要。本文就STAS的病理学、临床意义及影像学方面的研究进展予以综述。

The spread through air space(STAS)in lung cancer refers to the presence of tumor cells in the airway outside the main tumor body in the form of micropapillary cell clusters,solid cell nests,or individual cells.The researches of lung cancer in recent years discover the significant value of STAS for diagnosis,treatment,and prognosis,therefore the World Health Organization designated it as a new invasive pattern of lung adenocarcinoma in 2015.Predicting the presence of STAS by medicine imaging has been the research highlight in recent years.Though the feasibility of predicting STAS by medicine imaging has been confirmed,more in-depth researches are necessary for establishing more reliable and accurate prediction method in medicine imaging.This article reviews the research progresses of pathology,clinical significance and medicine imaging on STAS.