针刺治疗偏头痛的机制研究进展

Mechanism Research Progress on Acupuncture Therapy for Migraine

偏头痛(Migraine)作为一种发作性血管神经性疾病不仅严重危害着人们的身体健康,同时也对社会医疗经济产生巨大影响。针刺作为一种安全有效的治疗措施,在预防和缓解偏头痛急性发作方面被众多临床及动物实验证明是卓有成效的。然而,针刺治疗偏头痛的机制尚未完全明确。目前,围绕偏头痛的发生机制有3种较为主流的学说,分别是血管源性学说、神经源学说和三叉神经血管学说。近10年来相关研究针刺治疗偏头痛的文献表明,针刺可能通过减轻神经炎症、降低神经元致敏与调节脑功能网络连接等方式缓解疼痛,故探讨相关可能机制从而提出新的研究方向,有利于充实针刺治疗偏头痛的理论体系。

Migraine,as an episodic angioneurotic disease,not only seriously harms people's physical health,but also has a great impact on social medical economy.Acupuncture,as a safe and effective treatment measure,has been proved to be effective in preventing and relieving acute attack of migraine by many clinical and animal experiments.However,the mechanism of acupuncture in treating migraine is not fully understood.At present,there are three mainstream theories about the occurrence of migraine,which are angiogenic theory,neurogenic theory and trigeminal neurovascular theory.The literature on acupuncture treatment for migraine in recent 10 years showed that acupuncture might relieve pain by reducing nerve inflammation,reducing neuronal sensitization,regulating brain functional network connectivity and so on.Exploring related mechanisms and proposing new research directions will help to lay a solid foundation for acupuncture treatment for migraine.