城乡居民高尿酸血症患病率及相关因素分析

Prevalence rate and related factors in urban and rural residents with hyperuricemia

目的探究城乡居民高尿酸血症(hyperuricemia,HUA)患病率及相关因素分析。方法选取2020年1月至2023年1月三六三医院体检部360例受检者,根据受检人群常住地址将其分为城市和乡村居民,采集其人口学信息、生活习惯及合并基础病情况,测量其空腹血糖(fasting blood glucose,FBG)、血尿酸(serum uric acid,SUA)、体质指数(body mass index,BMI)、三酰甘油(triglyceride,TG)。采用logistic回归分析HUA的危险因素。结果城市、乡村居民HUA发病率分别为12.18%、12.88%;城市和乡村居民在受教育程度、职业、BMI、睡眠时间、饮酒、FBG及TG水平差异有统计学意义(P均<0.05);logistic回归分析显示,男性、BMI>24 kg/m^(2)、饮酒、慢性肾病是城市居民发生HUA的独立危险因素(P均<0.05);慢性肾病、FBG≥7.0 mmol/L及TG≥2.3 mmol/L是乡村居民发生HUA的独立危险因素(P均<0.05)。结论乡村居民更应该加强健康教育和血糖血脂控制,城市居民更应该注重合理运动,控制饮酒量,减少居民高尿酸血症的发生。

Objective To explore the prevalence rate and related factors of urban and rural residents with hyperuricemia(HUA).Methods A total of 360 subjects in physical examination department of Sanliusan Hospital from January 2020 to January 2023 were selected and divided into urban residents and rural residents according to their permanent residence addresses,and the demographic information,living habits and underlying diseases were collected.Fasting blood glucose(FBG),serum uric acid(SUA),body mass index(BMI)and triglyceride(TG)were measured.The risk factors of HUA were analyzed by logistics regression analysis.Results The incidence rates of HUA in urban and rural residents were 12.18%and 12.88%.There were statistically significant differences in education level,occupation,BMI,sleep time,alcohol drinking,FBG and TG between urban and rural residents(all P<0.05).Logistics regression analysis showed that male,BMI>24 kg/m^(2),alcohol drinking and chronic kidney disease were independent risk factors for HUA occurrence among urban residents(all P<0.05).Chronic kidney disease,FBG≥7.0 mmol/L and TG≥2.3 mmol/L were independent risk factors for hyperuricemia occurrence among rural residents(all P<0.05).Conclusion Rural residents should strengthen health education and blood glucose and lipid control,and urban residents should pay more attention to reasonable exercise,control alcohol consumption and reduce HUA occurrence.