吸烟和哮喘

Smoking and asthma

吸烟严重危害人类健康,吸烟相关的气道损伤与呼吸系统慢性炎症密切相关。哮喘是一种异质性疾病,其核心特征是气道炎症。烟草暴露是哮喘发病的危险因素。本文从吸烟对哮喘气道炎症、气道高反应性、气道重塑,以及吸入型糖皮质激素治疗等方面影响的角度,探讨吸烟与哮喘的关系。

Smoking is a serious hazard to human health,and smoking-related airway injury is closely related to chronic inflammations of the respiratory system.Asthma is a heterogeneous disease,presenting the airway inflammation as the main feature.Smoking-induced tobacco exposure is a risk factor for asthma.This paper aims to explore the relationship between smoking and asthma from the perspective of the effects of smoking on airway inflammation,airway hyperresponsiveness,airway remodeling and inhaled glucocorticoid therapy.