孙崎团队在新类型alpha 7 nAChR正向变构调节剂及其改善认知障碍功能方面获得新进展

The research group of Prof.Qi Sun has made new progress in the development of allosteric activation of a7 nicotinic acetylcholine receptors for the improvement of cognitive deficits

2024年2月23日,北京大学药学院天然药物及仿生药物全国重点实验室孙崎教授团队与青岛大学王克威教授团队合作在Journal of Medicinal Chemistry上在线发表了题为“Allosteric activation of α7 nicotinic acetylcholine receptors by novel 2-arylamino-thiazole-5-carboxylic acid amide derivatives for the improvement of cognitive deficits in mice”(新型2-芳氨基噻唑-5-酰胺类化合物变构增强α7尼古丁乙酰胆碱受体用于改善小鼠体内认知障碍)的研究工作。