^(125)I粒子近距离照射在口腔颌面部恶性肿瘤治疗中的临床应用进展

Progress in clinical application of ^(125)I seeds brachytherapy in the treatment of oral and maxillofacial malignant tumors

口腔颌面部恶性肿瘤威胁患者生命健康,严重影响患者的吞咽、语言功能和面容。其治疗方法中,^(125)I粒子近距离照射治疗技术因手术创伤小,靶区组织剂量大分布均匀,对周边正常组织损伤小,可以减少医护人员辐射暴露等优点,受到广泛关注。利用^(125)I粒子对口腔颌面部肿瘤进行持续、低剂量的近距离照射治疗,可以有效减小肿瘤体积,延长患者的生存期,治疗效果显著。该文针对^(125)I粒子近距离照射在口腔颌面部恶性肿瘤的临床应用展开综述。

Oral and maxillofacial malignant tumors threaten the life and health of patients,and seriously affect their swallowing,language function and face.^(125)I seeds brachytherapy for oral and maxillofacial malignant tumors has been widely concerned and studied because of its advantages such as less surgical trauma,large and uniform dose distribution in the target tissue,little damage to the surrounding normal tissue,and reducing radiation exposure of medical staff.Low-dose brachytherapy with ^(125)I seeds can effectively reduce the tumor volume and prolong the survival time of patients.This article reviews the clinical application of ^(125)I seeds brachytherapy in oral and maxillofacial malignant tumors.