植物活性成分对动物肠道屏障功能的调控作用及其机制

Advances in Regulation and Mechanism of Plant Bioactive Compounds on Intestinal Barrier Function in Animals

肠道不仅是动物机体消化、吸收营养物质的主要场所,同时也是机体发挥防御保护作用的重要组成部分之一,完整的肠道屏障可有效阻止抗原、细菌毒素和有害物质通过,对维持动物健康极为重要。近年来研究发现,天然植物活性成分(NPBCs)具有免疫调节、抑菌、抗氧化、改善肠道健康等多种生物学功能,在畜禽生产及疾病防治中有广泛的应用价值。本文就NPBCs对动物肠黏膜形态结构、肠道屏障功能以及肠道菌群结构的影响进行综述,旨在为深入了解NPBCs对动物肠道健康的调控作用及其在动物生产中的应用开发提供参考。

Intestinal tract is not only the largest and most complex organ in the animal body,but also the component of body′s defense forefront.The integrity of the intestinal barrier is extremely important for maintaining animal health,as it can effectively prevent the passage of antigens,bacterial toxins and harmful macromolecules.In recent years,it has been found that natural plant bioactive compounds(NPBCs)have many biological functions such as immune regulation,bacteriostasis,antioxidant,improving intestinal health,etc.,and have wide application value in livestock production and disease prevention and control.In this paper,the effects of NPBCs on intestinal morphology,intestinal barrier function and intestinal flora structure of animals were reviewed,aiming to provide references for further understanding of the regulatory effects of NPBCs on intestinal health and their application in animal production.