健中愈疡片治疗消化道溃疡出血的临床疗效及对胃肠电图影响分析

Clinical Efficacy of Jianzhong Yuyang Tablet in Treating Gastrointestinal Ulcer Bleeding and Its Influence on Gastroenteric Electroencephalogram

目的:分析健中愈疡片治疗消化道溃疡出血的临床疗效及对胃肠电图影响。方法:选定无锡市人民医院2021年8月至2023年8月就诊的106例消化道溃疡出血患者,根据治疗方法的不同将其分为2组,对比组52例给予常规西药对症治疗,观察组54例在对比组基础上给予健中愈疡片治疗,比较两组临床疗效、胃液pH值、血红蛋白(hemoglobin,Hb)、胃肠电图、血清炎症因子指标。结果:观察组临床总有效率(96.30%)高于对比组(76.92%)(P<0.05)。观察组治疗后胃液pH值、Hb均较对比组更高(P<0.05)。观察组治疗后胃体部、胃窦部、横结肠、降结肠、直肠平均幅值均较对比组更高(P<0.05)。观察组治疗后血清超敏C反应蛋白(hypersensitive C-reactive protein,hs-CRP)、白细胞介素-10(interleukin-10,IL-10)、IL-8水平均较对比组更低(P<0.05)。结论:健中愈疡片可有效改善消化道溃疡出血患者溃疡、出血等症状,提高Hb,调节胃肠电图,减轻炎症反应,疗效显著。

Objective:To analyze the clinical efficacy of Jianzhong Yuyang tablet in the treatment of gastrointestinal ulcer bleeding and its influence on gastroenteric electroencephalogram.Methods:A total of 106 patients with gastrointestinal ulcer bleeding treated in our hospital from August 2021 to August 2023 were selected and divided into 2 groups according to different treatment methods.52 cases in the comparison group were given conventional symptomatic treatment with Western medicine,and 54 cases in the observation group were given Jianzhong Yuyang tablet on the basis of the comparison group.The clinical efficacy,pH value of gastric fluid,hemoglobin(Hb),electrogastroenterogram and serum inflammatory factors were compared between the two groups.Results:The total clinical effective rate of observation group(96.30%)was higher than that of comparison group(76.92%)(P<0.05).After treatment,the pH and Hb of gastric juice in observation group were higher than those in comparison group(P<0.05).After treatment,the average amplitude of stomach body,gastric antrum,transverse colon,descending colon and rectum in observation group was higher than that in comparison group(P<0.05).The levels of hypersensitive C-reactive protein(hs-CRP),interleukin-10(IL-10)and IL-8 in the observation group after treatment were lower than those in the control group(P<0.05).Conclusion:Jianzhong Yuyang Tablet can effectively improve the symptoms of ulcer and bleeding in patients with gastrointestinal ulcer hemorrhage,increase Hb,regulate gastroenteric electroencephalogram,and reduce inflammation.