肺炎支原体流行病学特征及重症肺炎支原体肺炎临床特征

Epidemiological Characteristics of Mycoplasma Pneumoniae and Clinical Characteristics of Severe Pneumonia

目的 探讨肺炎支原体肺炎(Mycoplasma Pncumoniac Pncumonia,MPP)的流行病学特征及影响因素。方法回顾性选取2022年11月—2023年10月广西医科大学第二附属医院收治的50例肺炎患儿的临床资料,根据肺炎支原体抗体免疫球蛋白M(Immunoglobulin M,IgM)阳性结果将患儿分为MPP组(n=17)和非MPP组(n=33),比较两组患儿的临床特征。结果 两组住院时间、侵入性操作、白细胞计数、中性粒细胞比例、C反应蛋白以及降钙素原比较,差异有统计学意义(P均<0.05)。住院时间、侵入性操作、白细胞计数、中性粒细胞比例、C反应蛋白以及降钙素原属于肺炎患儿肺炎支原体肺炎发病的危险因素(OR=4.366、3.662、3.444、2.782、3.669、4.551,P均<0.05)。结论 住院时间、侵入性操作、白细胞计数、中性粒细胞比例、C反应蛋白以及降钙素原对肺炎支原体肺炎患儿具有很大的影响,建议在临床中加强此方面的关注,尽量减少其影响。

Objective To investigate the epidemiological characteristics and influencing factors of mycoplasma pneumoniae pneumonia(MPP).Methods The clinical data of 50 children with pneumonia admitted to the Second Affiliated Hospital of Guangxi Medical University from November 2022 to October 2023 were retrospectively selected.According to the positive results of Mycoplasma pneumoniae Immunoglobulin M(IgM),the children were divided into MPP group(n=17) and non-MPP group(n=33),and the clinical characteristics of the two groups were compared.Results There were statistically significant differences in length of hospital stay,invasive procedures,white blood cell count,neutrophil ratio,C-reactive protein and procalcitonin between the two groups(all P<0.05).Length of stay,invasive procedures,white blood cell count,neutrophil ratio,C-reactive protein and procalcitonin were risk factors for mycoplasma pneumoniae in children with pneumonia(OR=4.366,3.662,3.444,2.782,3.669,4.551,all P<0.05).Conclusion Length of hospital stay,invasive operation,white blood cell count,neutrophils ratio,c-reactive protein and calcitonin original children with mycoplasma pneumoniae pneumonia has a great influence,and Suggestions to strengthen the areas of concern in the clinical,to minimize the impact.