早期胃癌内镜下分型与浸润深度及淋巴结转移的关系分析

Relationship Analysis of Endoscopic Typing of Early Gastric Cancer with Infiltration Depth and Lymphatic Metastasis

目的:分析早期胃癌内镜下分型与浸润深度及淋巴结转移的关系。方法:选取2020年3月至2023年3月期间在我院就诊的103例早期胃癌患者为研究对象,收集患者一般临床资料,分析内镜下分型与浸润深度、淋巴结转移的关系。结果:103例患者中,男性占63.11%,女性占36.89%;平均年龄为(52.36±10.73)岁,平均肿瘤最大直径为(2.15±0.89)cm;肿瘤位置,上部、中部、下部分别占20.39%、50.49%、29.13%;胃癌分化程度,高分化、中分化、低分化分别占37.86%、43.69%、18.45%;Lauren分型,间质型、腺癌型分别占49.51%、50.49%;TNM分期,IA期、IB期分别占69.90%、30.10%;根据内镜分型,103例患者中Ⅰ型15例(14.56%),Ⅱ型64例(62.14%),Ⅲ型24例(23.30%),不同内镜分型肿瘤浸润深度差异有统计学意义(P<0.05),组间两两比较,Ⅰ型与Ⅱ型、Ⅲ型差异均有统计学意义(P=0.025、0.032),Ⅱ型与Ⅲ型差异有统计学意义(P=0.047);不同内镜分型淋巴结转移的检出率差异有统计学意义(P<0.05),组间两两比较,Ⅰ型低于Ⅱ型、Ⅲ型(P=0.028、0.015),Ⅱ型低于Ⅲ型(P=0.036)。结论:早期胃癌内镜下分型与浸润深度及淋巴结转移密切相关。

Objective:To analyze the relationship between endoscopic typing of early gastric cancer and infiltration depth and lymph node metastasis.Methods:103 patients with early gastric cancer admitted to the hospital from March 2020 to March 2023 were selected as the research subjects.General clinical data of pa-tients were collected and the relationship between endoscopic typing,infiltration depth and lymph node metas-tasis was analyzed.Results:Among the 103 patients,63.11%were males and 36.89%were females.The mean age was(52.36±10.73)years old and the mean maximum tumor diameter was(2.15±0.89)cm.The tumor locations were 20.39%in the upper part,50.49%in the middle part and 29.13%in the lower part.The differentiation degree of gastric cancer showed that there were 37.86%of high differentiation,43.69%of middle differentiation and 18.45%of low differentiation.Lauren typing revealed that interstitial type accoun-ted for 49.51%and adenocarcinoma type accounted for 50.49%respectively.In terms of TNM staging,IA stage and IB stage accounted for 69.90%and 30.10%.According to endoscopic typing,there were 15 cases(14.56%)of type I,64 cases(62.14%)of type II and 24 cases(23.30%)of type III among the 103 pa-tients.The differences in tumor infiltration depth among different endoscopic types were statistically significant(P<0.05).In pairwise comparisons between groups,the differences between Type I and both Type II and Type III were statistically significant(P=0.025 and 0.032,respectively),and the difference between Type II and Type III was also statistically significant(P=0.047).The differences in lymph node metastasis detec-tion rates among different endoscopic types were statistically significant(P<0.05).In pairwise comparisons,the rate for Type I was lower than that for Type II and Type III(P=0.028 and 0.015,respectively),and the rate for Type II was lower than that for Type III(P=0.036).Conclusion:Endoscopic typing of early gastric cancer is closely related to infiltration depth and lymph node metastasis.