妊娠期糖尿病孕妇妊娠结局的相关风险因素研究

Risk Factors for Pregnancy Outcomes in Pregnant Women with Gestational Diabetes Mellitus

目的探讨妊娠期糖尿病(Gestational Diabetes Mellitus,GDM)患者的妊娠结局相关影响因素,为临床早期干预提供依据。方法回顾性选取厦门市妇幼保健院于2020年1—12月收治的100例GDM患者的临床资料,依照最终的妊娠结局分成不良结局组和正常结局组,再行单因素、多因素Logistic回归分析,明确GDM不良妊娠结局的独立危险因素。结果不良妊娠结局25例(25.0%),正常妊娠结局75例(75.0%);通过单因素及多因素Logistic回归分析表明年龄、妊娠前体质指数、葡萄糖耐量试验指标异常及妊娠期血糖控制不佳是不良妊娠结局的独立危险因素(OR=2.232、3.235、2.119、3.336、3.577)。结论高龄、妊娠前超重、葡萄糖耐量试验指标全部异常及妊娠期血糖控制不佳直接关系到GDM的妊娠结局,应早识别、早干预,以改善妊娠结局,提高妊娠质量。

Objective To investigate the related influencing factors of pregnancy outcomes in patients with gestational diabetes mellitus(GDM),and to provide evidence for early clinical intervention.Methods The clinical data of 100 GDM patients admitted to Xiamen Maternal and Child Health Hospital from January to December 2020 were retro-spectively selected.According to the final pregnancy outcome,they were divided into adverse outcome group and nor-mal outcome group.Univariate and multivariate Logistic regression analysis was performed to identify the independent risk factors for adverse pregnancy outcome of GDM.Results There were 25 adverse pregnancy outcomes(25.0%)and 75 normal pregnancy outcomes(75.0%).Univariate and multivariate Logistic regression analysis showed that age,pre-pregnancy BMI,OGTT and poor glycemic control during pregnancy were independent risk factors(OR=2.232,3.235,2.119,3.336,3.577).Conclusion Advanced age,overweight before pregnancy,abnormal OGTT indicators and poor gestational blood glucose control during pregnancy are directly related to the pregnancy outcome of GDM,and early identification and intervention should be carried out to improve the pregnancy outcome and pregnancy quality.