糖尿病新生儿发生低血糖的危险因素分析

Analysis of Risk Factors for Hypoglycemia in Diabetic Neonates

目的分析糖尿病新生儿发生低血糖的危险因素。方法选取2021年6月—2023年10月晋江市医院(上海市第六人民医院福建医院)收治的80例糖尿病新生儿作为研究对象,根据患儿是否存在低血糖现象分为参照组(不存在低血糖,n=40)、观察组(存在低血糖,n=40)。检测患儿出生48 h血糖水平并开展问卷调查,从而进行单因素分析、Logistic多因素分析。结果Logistic回归分析结果显示,影响糖尿病新生儿出生后低血糖产生的因素较多,主要包括新生儿出生体质量、母亲年龄、母亲妊娠期增加体质量(P均<0.05)。结论糖尿病新生儿出生48 h内比较容易出现反复低血糖现象,其中新生儿出生体质量、母亲年龄、母亲妊娠期增加体质量均为糖尿病新生儿低血糖产生的独立影响因素,应重点关注该类新生儿并提供有效干预,降低其低血糖发生概率。

Objective To analyze the risk factors of hypoglycemia in diabetic neonates.Methods A total of 80 diabetic neonates admitted to Jinjiang Hospital(Fujian Hospital of Shanghai Sixth People's Hospital)from June 2021 to Octo-ber 2023 were selected as the study objects.They were divided into the reference group(no hypoglycemia,n=40)and the observation group(hypoglycemia,n=40)according to whether they had hypoglycemia.Blood suger of the children 48 h after birth was monitored,and questionnaire was applied to carry out univariate analysis and Logistic multivariate analysis.Results Logistic regression analysis showed that there were many factors affecting the generation of hypogly-cemia in neonates with diabetes mellitus after birth,including newborn birth weight,maternal age and increased ma-ternal body mass during pregnancy,and the differences were statistically significant(all P<0.05).Conclusion Diabetic neonates are more prone to recurrent hypoglycemia within 48 hours of birth,among which birth weight,maternal age and increased maternal body weight during pregnancy are all independent influencing factors for diabetic neonatal hy-poglycemia.Attention should be paid to these newborns and effective interventions should be provided to reduce the probability of hypoglycemia.