摘要
2022年美国髋关节和膝关节外科医师协会、美国骨科医师协会及美国局部麻醉与疼痛医学学会共同协作,针对氯胺酮在全关节置换术(TJA)中的应用疗效和安全性进行了循证研究。通过对多项研究的系统评价和Meta分析,得出以下结论:氯胺酮可有效减轻患者术后疼痛;氯胺酮可有效减轻患者术后恶心、呕吐的发生;氯胺酮可降低术后阿片类药物的使用;术中使用氯胺酮不会增加术后不良反应的发生率。并根据证据支持强度对以上结论进行了等级划分。本文对该指南进行解读,为解决在TJA中使用氯胺酮的有效性和安全性问题提供参考。
The American Association of Hip and Knee Surgeons,the American Academy of Orthopaedic Surgeons,and the American Society of Regional Anesthesia and Pain Medicine collaborated to develop an evidence-based study about the safe and effective use of Ketamine in total joint arthroplasty(TJA).Based on the systematic review and Meta-analysis of several studies,the following conclusions are drawn:Ketamine can effectively relieve the postoperative pain of patients;Ketamine can effectively reduce the occurrence of postoperative nausea and vomiting;Ketamine can reduce the use of postoperative opioids;intraoperative use of Ketamine does not increase the incidence of postoperative adverse reactions.The above conclusions are graded according to the strength of evidence support.This article interprets the guidelines to provide reference for addressing the effectiveness and safety of Ketamine use in TJA.
作者
王帆
许焕焕
马瑞
马宇杰
万贤杰
许珂
许鹏
Wang Fan;Xu Huanhuan;Ma Rui;Ma Yujie;Wan Xianjie;Xu Ke;Xu Peng(Medical School of Yan′an University,Yan′an 716000,China;Department of Joint Surgery,Honghui Hospital,Xi′an Jiaotong University,Xi′an 710054,China)
出处
《国际外科学杂志》
2024年第3期203-206,共4页
International Journal of Surgery
关键词
关节成形术
置换
氯胺酮
指南
医疗准则
Arthroplasty,replacement
Ketamine
Guidebookes
Medical guidelines
