摘要
In this paper,we have developed a decarboxylative amination of carboxylic acids with nitroarenes for the synthesis of secondary amines.The protocol is performed at mild conditions without the use of noble metals as catalysts.A wide range of structurally diverse secondary amines could be obtained in good yields(up to 94%)with good functional group tolerance.This transformation shows good to excellent selectivity,avoiding the generation of over alkylated byproducts.
基金
National Key Research and Development Program of China(2022YFA1503200,2021YFC2101901)
the National Natural Science Foundation of China(22122103,22101130,22001117,21971108,22271144)
Fundamental Research Funds for the Central Universities(020514380304,020514380252,020514380272)for financial support.
