肥胖相关肿瘤研究进展

Research progress of obesity-related tumors

肥胖通过促进慢性系统性炎症、高胰岛素血症、循环类固醇激素升高、血糖和脂质水平升高、促进细胞因子和生长因子的产生等方式促进恶性肿瘤的发生、发展。本文通过对国内外现有文献的回顾,对肥胖相关肿瘤的发生、发展的病理生理机制及减重手术预防肥胖相关肿瘤的现状进行总结。

Obesity can promote the development of tumors through accelerating chronic inflammation,hyperinsulinemia,hypercirculating steroid hormonemia,hypergycemia,hyperlipemia and the production of cytokines and growth factors.Herein,the recent literatures about the development of obesity-related tumors and the phenomenon of obesity paradox are reviewed briefly.And we summarize the current status of bariatric surgery to prevent obesity-related tumors.