艾盐包联合穴位贴敷、耳穴压豆对血液肿瘤化疗患者生活质量及不良反应的影响

Effect of Moxa-Salt Package Combined with Point Application and Auricular Point Pressure with Beans on Quality of Life and Adverse Reactions in Hematologic Tumor Patients Undergoing Chemotherapy

目的:观察艾盐包联合穴位贴敷、耳穴压豆对血液肿瘤化疗患者生活质量及不良反应的影响。方法:选取接受化疗治疗的150例血液肿瘤患者为研究对象,随机分为观察组及对照组各75例。2组均给予盐酸托烷司琼注射液、异甘草酸镁注射液、人血白蛋白等常规治疗,观察组加用艾盐包联合穴位贴敷、耳穴压豆治疗。比较2组临床疗效、化疗不良反应发生情况,以及2组治疗前后Herth希望量表(HHI)、生活质量测定量表(QLICP-LE)评分变化。结果:观察组总有效率为80.00%,对照组为62.67%,2组比较,差异有统计学意义(P<0.05)。观察组胃肠道不良反应发生率为60.00%,对照组为77.33%,2组比较,差异有统计学意义(P<0.05)。2组骨髓抑制、黏膜毒性反应、肝肾损害、过敏及其他反应发生率比较,差异无统计学意义(P>0.05),观察组恶心呕吐总发生率为46.67%,对照组为66.67%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组HHI、QLICP-LE评分均较治疗前升高(P<0.05),且观察组HHI、QLICP-LE评分均高于对照组(P<0.05)。结论:常规西药联合艾盐包、穴位贴敷、耳穴压豆可提高血液肿瘤患者的化疗态度及生存信念,降低恶心呕吐发生率,改善生活质量,临床疗效确切。

Objective:To observe the effect of the therapy of moxa-salt package combined with point application and auricular point seed-pressing on the quality of life and adverse reactions in hematologic tumor patients undergoing chemotherapy.Methods:A total of 150 patients with hematologic tumors undergoing chemotherapy were randomly divided into the observation group and the control group,with 75 patients in each group.The two groups were treated with Tropisetron Hydrochloride Injection,Magnesium Isoglycyrrhizinate Injection and Human Blood Albumin,and the observation group was additionally treated with moxa-salt package combined with point application and auricular point seed-pressing.The incidence of chemotherapy adverse reactions,scores of Herth Hope Index(HHI)and Quality of Life Instruments for Cancer Patients-Leukemia(QLICP-LE)were compared between the two groups.Results:The total effective rate was 80.00%in the observation group and 62.67%in the control group,the difference being significant(P<0.05).The incidence of gastrointestinal adverse reactions was 60.00%in the observation group and 77.33%in the control group,the difference being significant(P<0.05).There was no significant difference in the incidence of myelosuppression,mucosal toxicity,liver and kidney damage,allergy and other reactions between the two groups(P>0.05).The total incidence of nausea and vomiting was 46.67%in the observation group and 66.67%in the control group,the difference being significant(P<0.05).After treatment,the HHI and QLICP-LE scores in the two groups were increased when compared with those before treatment(P<0.05),and the HHI and QLICP-LE scores in the observation group were higher than those in the control group(P<0.05).Conclusion:The therapy of conventional western medicine combined with moxa-salt package,point application and auricular point seed-pressing can reduce the incidence of chemotherapy nausea and vomiting in hematologic tumor patients undergoing chemotherapy,improve the quality of life,enhance their chemotherapy attitude and survival belief,andhave a definite clinical effect.