胸腔镜下肺癌根治术对患者肺功能的影响

Effect of thoracoscopic radical resection of lung cancer on lung function of patients

目的分析胸腔镜下肺癌根治术治疗后患者肺功能的变化情况。方法选取2018年4月-2021年4月于聊城市茌平区人民医院接受肺癌根治术治疗的80例患者进行研究,所有患者均接受病理检查确诊为病理分期Ⅰ~Ⅱ期的早期肺癌,均有手术指征,以随机抽签法将其分为对照组和研究组,各40例。对照组接受开胸肺癌根治术治疗,研究组接受胸腔镜下肺癌根治术治疗。比较两组患者肺功能指标(最大通气量、用力肺活量及1 s内用力呼气量)、手术情况(手术时间、术中失血量、淋巴结清扫个数及住院时间)、术后转移及复发率。结果术前,两组患者肺功能各指标比较差异无统计学意义(P>0.05);术后,研究组患者肺功能各指标均高于对照组,差异均有统计学意义(P<0.05)。研究组患者手术时间为(156.49±27.16)min,短于对照组的(178.46±33.07)min;术中失血量为(173.24±15.57)mL,少于对照组的(284.16±37.19)mL;淋巴结清扫个数为(15.34±1.12)个,多于对照组的(14.26±2.18)个;住院时间为(12.26±3.14)d,短于对照组的(15.83±3.61)d,差异均有统计学意义(P<0.05)。两组术后转移及复发率比较差异无统计学意义(P>0.05)。结论胸腔镜下肺癌根治术治疗相较开胸手术治疗而言,对患者肺功能造成的影响相对更小,手术时间、住院时间更短,淋巴结清扫个数更多,适合在临床中加以推广。

Objective To analyze the changes of lung function after thoracoscopic radical resection of lung cancer.Methods A total of 80 patients who underwent radical resection of lung cancer in Chiping District People's Hospital from April 2018 to April 2021 were selected for study.They all underwent pathological examination and were diagnosed as early lung cancer with pathological stage Ⅰ-Ⅱ.All of them had surgical treatment indications.They were divided into control group and study group by random lottery method,with 40 cases in each group.The control group received radical thoracotomy for lung cancer,while the study group received radical resection of lung cancer under thoracoscopy.The pulmonary function indexes(maximum ventilation,forced vital capacity and forced expiratory volume within 1 second),operation conditions(operation time,intraoperative blood loss,number of lymph node dissections and hospital stay),postoperative metastasis and recurrence rate were compared between the two groups.Results Before operation,there was no statistical significance in pulmonary function indexes between the two groups(P>0.05).After operation,the pulmonary function indexes of the study group were higher than those of the control group,and the differences were statistically significant(P<0.05).The surgical time of the study group patients was(156.49±27.16)minutes,which was shorter than that of the control group with(178.46±33.07)minutes;the intraoperative blood loss was(173.24±15.57)mL,which was lower than that of the control group with(284.16±37.19)mL;the number of lymph node dissection was(15.34±1.12),which washigher than that of the control group with(14.26±2.18);the length of hospital stay was(12.26±3.14)days,which was shorter than that of the control group with(15.83±3.61)days;and the differences were statistically significant(P<0.05).There was no significant difference in postoperative metastasis and recurrence rate between the two groups(P>0.05).Conclusion Compared with thoracotomy,thoracoscopic radical resection of lung cancer had less impact on patients'lung function,shorter operation time and hospital stay,and more lymph node dissections.It was suitable to be popularized in clinic.