“肠神共治”针刺法治疗孤独症谱系障碍的临床疗效观察

Clinical Efficacy of Acupuncture with"Intestine-spirit Joint Therapy"in Treating Autism Spectrum Disorders

目的:观察“肠神共治”针刺疗法对孤独症谱系障碍(autism spectrum disorder, ASD)的临床疗效。方法:将64例ASD患儿随机分为观察组和对照组,对照组32例(脱落2例),观察组32例(脱落1例)。对照组进行常规康复训练,具体为应用行为分析法、感觉统合训练、言语治疗、重复经颅磁治疗;观察组在对照组的基础上,加用基于“脑-肠轴”理论的“肠神共治”针刺疗法。4 w为1个疗程,予以6个疗程治疗。分别于治疗前、后比较2组患儿孤独症行为量表(ABC)、儿童孤独症评定量表(CARS)、胃肠疾病中医症状评分、孤独症治疗评估量表(ATEC)各项评分。结果:观察组总有效率为87.1%,对照组为63.3%,观察组患者总有效率高于对照组(P<0.05)。治疗后,2组患儿ABC、CARS、胃肠疾病中医症状及ATEC各项评分均较同组治疗前下降(P<0.05),且观察组低于对照组(P<0.05)。结论:联合应用“肠神共治”针刺疗法及常规康复训练,可有效缓解ASD患儿的临床症状以及胃肠功能问题。

Objective:To observe the clinical efficacy of acupuncture with"Intestine-spirit Joint Therapy"on autism spectrum dis-order(ASDs)Methods:Sixty-four children with ASDs were randomly divided into an observation group and a control group,with 32 cases in the control group(2 cases lost)and 32 cases in the observation group(1 case lost)The control group received routine rehabil-itation training,specifically behavioral analysis,sensory integration training,speech therapy,and repetitive transcranial magnetic ther-apy;On the basis of the control group,the observation group was treated with acupuncture with"Intestine-spirit Joint Therapy"based on the brain-gut axis theory.A course of treatment lasts for 4 weeks,and a total of 6 courses of treatment will be a dministered.The scores of the Autism Behavior Checklist(ABC),Childhood Autism Rating Scale(CARS),Traditional Chinese Medicine Symptom Score for gastrointestinal diseases(TCMSS),and Autism Treatment Evaluation Checklist(ATEC)were compared between the two groups before and after treatment Results:The total effective rate of the observation group was 871%,while that of the control group was 633%The total effective rate in the observation group was higher than that of the control group(P<005)After treatment,the scores of ABC,CARS,TCMSS,and ATEC in both groups decreased compared to the same group before treatment(P<005),and the observa-tion group was lower than the control group(P<005)Conclusion:The combined application of acupuncture with"Intestine-spirit Joint Therapy"and routine rehabilitation training can effectively alleviate the clinical symptoms and gastrointestinal function problems of children with ASDs.