大内科住院患者多种耐药菌感染的病原学分布特点及耐药性分析

Etiological distribution characteristics of multiple drug-resistant bacteria infection and drug resistance in inpatients in the internal medicine department

目的:分析大内科住院患者多种耐药菌感染的病原学分布特点及耐药性。方法:对2022年1月至2023年7月于我院大内科住院期间发生耐药菌感染的62例患者进行耐药菌培养及药敏实验,分析耐药菌感染的病原学分布特点及耐药性。结果:大内科住院62例患者共检出124株耐药菌,其中革兰阴性菌共101株占比81.45%,革兰阳性菌共23株,占比18.55%。痰液标本中共检出100株耐药菌,灌洗液标本中共检出10株耐药菌;尿液标本中共检出6株耐药菌,血液及分泌物标本中共检出8株耐药菌。主要革兰阴性菌均对亚胺培南、美罗培南耐药;主要革兰阳性菌对苯唑西林耐药。结论:在对我院大内科住院患者进行治疗时应根据耐药菌的分布特点和耐药性合理用药,保证药物的治疗有效性。

Objective:To analyze etiological distribution characteristics of multiple drug-resistant bacteria infections and drug resistance in internal medicine department patients.Methods:The drug-resistant bacteria culture and drug sensitivity tests were performed on 62 inpatients with drug-resistant bacteria infection in the internal medicine department of the hospital between January 2022 and July 2023.Etiological distribution characteristics of multiple drug-resistant bacteria infections and drug resistance were analyzed.Results:In the 62 inpatients in the internal medicine department,there were 124 strains of drug-resistant bacteria,including 101 strains of Gram-negative bacteria(81.45%)and 23 strains of Gram-positive bacteria(18.55%).In sputum samples,there were 100 strains of drug-resistant bacteria.In lavage fluid samples,there were 10 strains of drug-resistant bacteria.In urine samples,there were 6 strains of drug-resistant bacteria.In blood and secretion samples,there were 8 strains of drug-resistant bacteria.The main Gram-negative bacteria were resistant to imipenem and meropenem,while the main Gram-positive bacteria were resistant to oxacillin.Conclusion:In treating inpatients in the internal medicine department,rational medication should be taken according to distribution characteristics and drug resistance of drug-resistant bacteria to ensure the effectiveness of drug treatment.