A型肉毒素不同分区多点注射对下睑纹改善中的美学效果及安全性分析

Analysis of the aesthetic effect and safety of multi-point injection of botox type A in different zones in improving the lower palpebral striae

目的:探究A型肉毒素(Botulinum toxin A for therapeutic use,BTXA)不同分区多点注射对下睑纹改善中的美学效果及安全性。方法:选取2021年6月至2022年7月期间本院门诊收治的存在下睑纹的患者180例作为研究对象,随机分成对照组和观察组,每组90例。对照组采用BTXA三点注射法,观察组采用BTXA不同分区多点注射法,治疗时长m。比较两组的瘙痒程度、下睑纹改善情况、美学效果(Global aesthetic improvement scale,GAIS)、不良反应和满意度。结果:观察组瘙痒评分高于对照组(P<0.05);与治疗前相比,两组的皱纹分级评分降低,GAIS评分增加(P<0.05),其中观察组更为显著(P<0.05);观察组不良反应发生率低于对照组(P<0.05);观察组的满意率高于对照组(P<0.05)。结论:采用BTXA不同分区多点注射相比于三点注射具有更高的疗效、美学效果和安全性,提高患者满意度。

Objective:To explore the aesthetic effect and safety of multi-point injection of Botulinum toxin A for therapeutic use(BTXA)in improving lower palpebral striae.Methods:A total of 180 patients with lower palpebral striae admitted to the outpatient department of our hospital from June 2021 to July 2022 were selected as research objects and randomly divided into control group and observation group,with 90 cases in each group.The control group was treated with three-point injection of BTXA,and the observation group was treated with multi-point injection of different zones of BTXA for 6 months.The degree of pruritus,improvement of lower palpebral striae,Global aesthetic improvement scale(GAIS),adverse reactions and satisfaction were compared between the two groups.Results:The itch score of observation group was higher than that of control group(P<0.05).Compared with before treatment,the score of wrinkle grade decreased and GAIS score increased in both groups(P<0.05),especially in observation group(P<0.05).The incidence of adverse reactions in observation group was lower than that in control group(P<0.05).The satisfaction rate of observation group was higher than that of control group(P<0.05).Conclusion:Compared with three-point injection,multi-point injection with different zones of BTXA has higher efficacy,aesthetic effect and safety,and can improve patient satisfaction.