姜辛温肺汤联合磁热疗法治疗感染后咳嗽(寒饮伏肺证)的临床观察

Clinical Observation of Jiangxin Wenfei Decoction Combined with Magnetic Heat Therapy in the Treatment of Post Infectious Cough(Syndrome of Cold Fluid Retained in Lung)

目的观察姜辛温肺汤联合磁热疗法应用于感染后咳嗽(寒饮伏肺证)患者的临床疗效。方法选取感染后咳嗽(寒饮伏肺证)患者120例,使用随机数字表方法随机分为阿斯美组、姜辛温肺汤组、联合组各40例。阿斯美组给予阿斯美治疗,姜辛温肺汤组采用姜辛温肺汤进行治疗,联合组采用姜辛温肺汤加减联合磁热治疗,比较各组治疗效果、治疗前后中医证候积分、咳嗽平均起效时间、治疗前后外周血白细胞介素-8(IL-8)水平及不良反应。结果联合组总有效率为92.50%,明显高于阿斯美组的82.50%(P<0.05),稍高于姜辛温肺汤组的87.50%,差异无统计学意义(P>0.05)。治疗后,联合组较其他两组中医证候积分及外周血IL-8水平下降更多(P<0.05),咳嗽平均起效时间更快(P<0.05),且不良反应较少。结论姜辛温肺汤联合磁热疗法治疗较单纯西医治疗及单纯中药内服治疗感染后咳嗽(寒饮伏肺证)患者疗效更好。

Objective:To observe the clinical effect of Jiangxin Wenfei Decoction combined with magnetic heat therapy applied for post infectious cough(syndrome of cold fluid retained in lung).Methods:Totally 120 patients with post infectious cough(syndrome of cold fluid retained in lung)were selected and randomly divided into the Asmeton group,Jiangxin Wenfei Decoction group and combined group using random number table method,40 cases in each group.The Asmeton group was treated with Asmeton,the Jiangxin Wenfei Decoction group was treated with Jiangxin Wenfei Decoction,and the combined group was treated with modified Jiangxin Wenfei Decoction combined with magnetic heat therapy.The treatment effect,TCM pattern score before and after treatment,mean onset time of cough,peripheral blood IL-8 level and adverse reactions before and after treatment were compared between the groups.Results:The total effective rate of the combined group was 92.50%,which was significantly higher than 82.50%of the Asmeton group(P<0.05)and slightly higher than 87.50%of the Jiangxin Wenfei Decoction group,but the difference was not statistically significant(P>0.05).After treatment,the TCM syndrome score and peripheral blood IL-8 level in the combined group decreased more than those in the control group(P<0.05),the average onset time of cough was faster(P<0.05),and there were fewer adverse reactions.Conclusion:Jiangxin Wenfei Decoction combined with magnetic heat therapy has better efficacy in the treatment of patients with post-infection cough(syndrome of cold fluid retained in lung)than western medicine alone or Chinese medicine alone.