金属组学与胃癌的关系及其研究进展

The Relationship and Research Progress between Metallomics and Gastric Cancer

随着金属组学的发展,其在胃癌(GC)早期诊断和治疗中的作用日益受到关注。维持微量元素如铁、锌、钙和铜的正常含量和代谢对GC的预防和治疗具有重要意义。对中、晚期GC患者来说,以金属抗癌药物为主的化学药物治疗和靶向治疗可以明显提高患者的生存期和生活水平。文章从金属抗癌药物在GC治疗中的作用、微量元素在GC治疗中的作用和金属组学在GC早期诊断中的作用三个方面进行总结,综述金属组学与GC的关系及其研究进展。

With the development of metallomics,its role in the early diagnosis and treatment of GC has attracted more and more attention.Maintaining the normal content and metabolism of trace elements such as iron,zinc,calcium and copper is important for the prevention and treatment of GC.For patients with intermediate and advanced GC,chemical therapy and targeted therapy with metal anticancer drugs can significantly improve the survival and living standards of patients.This paper summarizes the role of metal anticancer drugs in the treatment of GC,the role of trace elements in the treatment of GC and the role of metallomics in the early diagnosis of GC and illustrates the relationship between metallomics and GC as well as its research progress.