PPIs用药规则在前置审方软件中的精细化管理

Refined management of PPIs medication rules in prescription pre-review software

目的分析质子泵抑制剂(PPIs)用药规则的精细化设置在处方前置审核中的应用成效,促进PPIs药物的合理应用。方法借助某院“处方前置审核软件”的审核规则,根据治疗幽门螺杆菌的临床实际用药情况,对PPIs在不同适应证下的用法用量、用药疗程以及特殊人群用药等规则进行精细化设置。分析评价幽门螺杆菌用药规则的建立对2022年1月~12月消化科门诊幽门螺杆菌用药处方审核及干预的影响。结果处方前置审核的PPIs用药问题处方占比和事后PPIs用药处方占比、处方不合格率呈下降趋势;事后PPIs处方适宜性呈上升趋势。结论PPIs用药规则维护在前置审方软件中的精细化设置可促进幽门螺杆菌用药的规范性,提高该院治疗幽门螺杆菌的规范性和合理用药率,保障患者的用药安全。

Objective To analyze the application effect of refined drug use rules for proton pump inhibitors(PPIs)in pre-prescription review,and promote the rational application of PPIs drugs.Methods Based on the review rules of a hospital's"prescription pre-review software",the usage and dosage,treatment courses,and special population medication rules of PPIs under different indications were refined according to the actual clinical medication situation for treating Helicobacter pylori.Analyze and evaluate the impact of the establishment of medication rules for Helicobacter pylori on the review and intervention of Helicobacter pylori medication prescriptions in gastroenterology clinics from January 2022 to December 2022.Results The proportion of PPIs with medication issues in the pre-review of prescriptions,the proportion of PPIs with medication prescriptions after the review,and the prescription unqualified rate show a downward trend;the appropriateness of PPIs prescriptions after the review was increased.Conclusion The refined setting of PPIs medication rules maintenance in the prescription pre-review software can promote the standardization of Helicobacter pylori medication,improve the standardization and reasonable medication rate of the hospital's treatment of Helicobacter pylori,and ensure the safety of patients'medication.