三七茎叶提取物对断奶仔猪生长性能、血清生化指标和肠道健康的影响

Effects of Panax notoginseng stems and leaves extract on growth performance,serum biochemical indexes and intestinal health of weaned piglets

试验旨在研究三七茎叶提取物对断奶仔猪生长性能、血清生化指标和肠道健康的影响。选取26日龄断奶仔猪24头随机分为3组,每组8个重复,每个重复1头仔猪。对照组饲喂基础饲粮,低剂量组、高剂量组分别在基础饲粮中添加0.2%和0.4%的三七茎叶提取物。试验期21 d。结果显示,与对照组相比,高剂量组断奶仔猪平均日增重显著升高(P<0.05),低剂量组和高剂量组血清乳酸脱氢酶活性、谷草转氨酶活性和谷草/谷丙的比值显著降低(P<0.05);高剂量组断奶仔猪十二指肠、空肠、回肠的绒毛高度显著增加(P<0.05),十二指肠和回肠的绒隐比显著升高(P<0.05);低剂量组和高剂量组结肠白细胞介素-12 p35(IL-12 p35)、白细胞介素-12 p40(IL-12 p40)、肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)和干扰素-γ(IFN-γ)的mRNA表达量显著降低(P<0.05)。研究表明,在饲粮中添加三七茎叶提取物可以改善断奶仔猪生长性能、肠道健康,添加0.4%三七茎叶提取物较为适宜。

The purpose of the experiment was to study the effects of Panax notoginseng stems and leaves extract on the growth performance,serum biochemical indexes,and intestinal health of weaned piglets.Twenty-four 26-day-old weaned piglets were randomly divided into three groups with eight replicates in each group and one piglet in each replicate.The control group was fed with a basal diet,while the low dose group and high dose group were fed with 0.2%and 0.4%of Panax notoginseng stems and leaves extract,respectively.The trial period was 21 days.The results showed that compared with the control group,the average daily gain of weaned piglets in the high dose group increased significantly(P<0.05),while the activities of lactate dehydrogenase,aspartate oxaloacetic aminotransferase,and the ratio of aspartate oxaloacetic aminotransferase to aspartate oxaloacetic aminotransferase in the low and high dose groups decreased significantly(P<0.05).The high dose group could significantly increase the villus height of duodenum,jejunum,and ileum(P<0.05),and significantly increase the villus-concealed ratio of duodenum and ileum(P<0.05).The mRNA expression of colonic interleukin-12 p35(IL-12 p35),interleukin-12 p40(IL-12 p40),tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1β),and interferon-γ(IFN-γ)decreased significantly in the low dose group and high dose group(P<0.05).The results show that adding Panax notoginseng stems and leaves extract in diet can improve the growth performance and intestinal health of weaned piglets,and adding 0.4%Panax notoginseng stems and leaves extract is more suitable.