2004—2021年中国支气管扩张相关的死亡特征分析

The analysis on the death characteristics related to bronchiectasis in China from 2004 to 2021

目的 分析2004—2021年中国与支气管扩张相关的死亡特征,为制定呼吸系统疾病防治策略提供参考。方法 数据来源于2004—2012年全国疾病监测系统以及2013—2021年全国人口死亡信息登记管理系统,纳入死因链中死亡原因包括支气管扩张的所有死亡个案。采用SAS 9.4软件进行χ^(2)检验,采用Joinpoint 4.8.0.1软件计算平均年度变化百分比(AAPC)。结果 2004—2021年支气管扩张相关的年均死亡率为0.85/10万,标化后死亡率呈波动趋势,变化趋势无统计学意义(AAPC=0.84%,P>0.05)。男性支气管扩张相关的年均死亡率(0.96/10万)高于女性(0.73/10万),城市人群支气管扩张相关的年均死亡率(1.15/10万)高于农村人群(0.64/10万),差异均有统计学意义(P<0.01),且城市人群支气管扩张相关标化死亡率随年份呈上升趋势(AAPC=2.60%,P<0.05)。东部和西部地区年均死亡率显著高于中部地区,差异均有统计学意义(P<0.01),且西部地区标化死亡率上升较快(AAPC=3.20%,P<0.01)。支气管扩张相关死亡个案中,主要的根本死因为支气管扩张(73.92%),其次为慢性阻塞性肺疾病(5.94%)和慢性支气管炎(4.67%)。结论 中国支气管扩张相关的死亡率存在区域和性别差异,应采取针对性的预防策略,重点关注西部地区、城市以及男性人群。

Objective To analyze the the death characteristics related to bronchiectasis in China from 2004 to 2021,and provide the reference for formulating the strategies of the prevention and treatment of respiratory diseases.Methods The data were from“The national disease surveillance system from 2004 to 2012”and“The National population death information registration and management system from 2013 to 2021”,the death causes included in the causes of death chain concluded all death cases including bronchiectasis.Theχ2 test was used to analyze the data,and JoinPoint 4.8.0.1 was used to calculate AAPC.The used software was SAS 9.4.Results The average annual bronchiectasis-related mortality from 2004 to 2021 was 0.85/105.The standardized mortality showed fluctuation(AAPC=0.84%,P>0.05).The average annual bronchiectasis-related mortality(0.96/105)in males was significantly higher than that(0.73/105)in females;the average annual bronchiectasis-related mortality(1.15/105)in urban area was significantly higher than that(0.64/105)in rural area,P<0.01.Moreover,the bronchiectasis-related standardized mortality showed uptrend with year(AAPC=2.60%,P<0.05).The average annual bronchiectasis-related mortality rates in eastern and western parts in China were significantly higher than that in middle part(P<0.01).Moreover,the average annual bronchiectasis-related mortality in western part increased quickly(AAPC=3.20%,P<0.01).In bronchiectasis-related cases,the main death causes were bronchiectasis(73.92%),chronic obstructive pulmonary disease(5.94%)and chronic bronchitis(4.67%).Conclusion There are regional and gender differences in bronchiectasis-related mortality in China.Targeted prevention strategies should be taken.It should pay attention to the western region,urban area and males.