早期食管癌患者ESD后并发症危险因素分析

Analysis of risk factors for postoperative complications in early esophageal cancer patients after ESD

目的探讨早期食管癌患者内镜黏膜下剥离术(ESD)后并发症危险因素。方法选取2021年1月至2023年4月该院收治的82例早期食管癌患者,根据术后并发症发生情况将其分为对照组(50例)和研究组(32例),比较2组临床特征,分析早期胃癌患者ESD后并发症危险因素。结果2组在年龄、糖尿病病史、肿瘤组织浸润深度、肿瘤长径、手术时间、术后创面、固有肌层损伤、血小板计数(PLT)方面比较,差异有统计学意义(P<0.05)。年龄(≥60岁)、合并糖尿病、肿瘤长径(<20 mm)、手术时间(≥45 min)、PLT(≥300×10^(9)L^(-1))、肿瘤组织浸润深度(m3+sm1)为ESD后并发症的危险因素(P<0.05)。结论年龄、合并糖尿病、肿瘤长径、手术时间、PLT、肿瘤组织浸润深度为早期食管癌患者ESD后并发症的危险因素,临床可根据上述因素筛选高危患者并加强随访,从而降低ESD后并发症发生率。

Objective To explore the risk factors for complications after endoscopic submucosal dissection(ESD)in early esophageal cancer patients.Methods A total of 82 patients with early esophageal cancer admitted to the hospital from January 2021 to April 2023 were selected and divided into the control group(50 cases)and the study group(32 cases)based on the incidence of postoperative complications.Clinical characteristics of the two groups were compared to analyze the risk factors of complications after ESD in the patients with early gastric cancer.Results There were statistically significant differences in terms of age,diabetes history,tumor tissue invasion depth,tumor diameter,operation time,postoperative wound,intrinsic muscle layer injury,and platelet(PLT)count between the two groups(P<0.05).Age(≥60 years old),diabetes,tumor diameter(<20 mm),operation time(≥45 min),PLT(≥300×10^(9) L^(-1)),tumor tissue invasion depth(m3+sm1)were risk factors for complications after ESD(P<0.05).Conclusion Age,diabetes,tumor diameter,operation time,PLT,and tumor tissue invasion depth are risk factors for postoperative complications of early esophageal cancer patients after ESD.Clinically,high-risk patients can be screened according to the above factors and follow-up can be strengthened to reduce the incidence of postoperative complications of ESD.