基于血流动力学的颅内动脉瘤破裂风险预测研究进展

Research progress on risk prediction of intracranial aneurysm rupture based on hemodynamics

颅内动脉瘤是常见的脑血管疾病之一,其破裂是造成自发性蛛网膜下腔出血的主要病因。针对未破裂颅内动脉瘤的破裂风险开展预测评估至关重要。作者回顾和整理了近年来国内外相关文献,围绕形态学、血流动力学因素对颅内动脉瘤破裂风险的预测展开综述,介绍了颅内动脉瘤成像和基于图像进行血流动力学建模的常用方法,讨论了建模关键步骤和常见误差来源,以期为颅内动脉瘤破裂风险评估提供一定参考。

Intracranial aneurysm is one of the common cerebrovascular diseases,and its rupture is the main cause of spontaneous subarachnoid hemorrhage.It is crucial to conduct predictive assessment on the rupture risk of unruptured aneurysms.The authors reviewed relevant domestic and foreign literatures in recent years on the prediction of intracranial aneurysm rupture risk based on morphological and hemodynamic factors,introduced commonly used methods for intracranial aneurysm imaging and hemodynamic modeling based on images,and discussed key steps and common errors in modeling in order to provide references for intracranial aneurysm rupture risk assessment.