摘要
患者,女,48岁。左膝结节16个月。患者曾在外院接受伊曲康唑及氨苯砜治疗9个月,无效。患者在我院通过皮肤组织分枝杆菌培养和定量聚合酶链反应(qPCR)测序技术诊断为海分枝杆菌感染,口服利福平和克拉霉素治疗4个月,皮损明显好转。患者从出现皮肤症状到诊断为海分枝杆菌感染的时间为16个月,提醒皮肤科临床医生应注意海分枝杆菌感染的非典型临床表现。
A 48-year-old female presented with nodules on the left knee for 16 months.The patient had been treated with itraconazole and dapsone in another hospital for 9 months,with ineffective.The patient was diagnosed with Mycobacterium marine infection by mycobacterium culture and quantitative polymerase chain reaction(qPCR)technique of skin tissue in our hospital.After 4 months of oral rifampicin and clarithromycin,the skin lesions were significantly improved.The time from the onset of skin symptoms to the diagnosis of mycobacterium marine infection was 16 months,which reminds dermatologists should be aware of the atypical clinical manifestations of Mycobacterium marinum infection.
作者
于越乾
暴芳芳
刘红
张福仁
YU Yueqian;BAO Fangfang;LIU Hong;ZHANG Furen(Hospital for Skin Diseases,Shandong First Medical University,Jinan 250022,China;Shandong Provincial Institute of Dermatology and Venereology,Shandong Academy of Medical Sciences,Jinan 250022,China)
出处
《中国麻风皮肤病杂志》
2024年第6期425-427,共3页
China Journal of Leprosy and Skin Diseases
基金
山东第一医科大学学术提升计划(编号:2019LJ002)。
关键词
海分枝杆菌感染
持久性隆起性红斑
误诊
Mycobacterium marinum infection
erythema elevatum diutinum
misdiagnose