补肾化痰方治疗原发性肝癌初探

An analysis of treating primary liver cancer with the Bushen Huatan prescription

原发性肝癌严重威胁着人们的生命和健康,尽管目前随着乙型病毒性肝炎疫苗的普遍推广,乙型病毒性肝炎患者人数明显下降,但是由于乙型病毒性肝炎患者群体基数巨大,因此我国原发性肝癌发病率仍然很高,而原发性肝癌一旦确诊,整体来说预后仍然不佳。随着理论研究的深入以及实验研究的广泛开展,原发性肝癌的西医治疗取得了长足的进步。近年来,随着经血管介入治疗、局部消融治疗和靶-免联合治疗在肝癌治疗中的快速发展,肝癌患者的生存时间和生活质量得到了大幅提升。中医药是肝癌综合治疗中非常重要的一部分。对于那些拒绝接受西医治疗的患者,单独使用中药治疗可以达到明显的改善症状、延长生存期的作用。在西医治疗的同时配合恰当中药治疗,可以达到明显减轻西医治疗毒性、增强西医治疗效果的作用。笔者团队长期从事恶性肿瘤的临床诊疗工作,对肝癌的中西医结合治疗进行了长期观察和积累,并广泛查阅古今文献,和院内外专家反复交流,通过对经典名方鳖甲煎丸进行分析与改进,逐渐拟定补肾化痰方,以此为基本方,根据临床证候不同进行加减化裁,在肝癌治疗上获得了一定疗效,显示出一定的临床推广价值。文章对几则典型病例进行汇报与分享,并进行理论探讨,为后续的实验研究乃至临床研究提供参考。

Primary liver cancer is a serious threat to our people’s life and health.Although the number of hepatitis B patients has decreased significantly with the universal promotion of hepatitis B vaccine,the incidence of primary liver cancer in China is still very high due to the huge population base of hepatitis B patients.Once primary liver cancer is diagnosed,the overall prognosis is still poor.In recent years,with the deepening of theoretical research and the extensive development of experimental research,Western medicine has made great progress in the treatment of primary liver cancer.In recent years,with the rapid development of transvascular interventional therapy,local ablation therapy and target-immunotherapy in the treatment of liver cancer,the survival time and quality of life of patients with liver cancer have been greatly improved.Traditional Chinese medicine is a very important part of the comprehensive treatment of liver cancer.For those patients who refuse to receive Western medicine,the use of TCM alone can significantly relieve symptoms and prolong survival.Western medicine plus appropriate TCM treatment can achieve significant effects of reduction in the toxicity and increase in clinical efficacy of Western medicine.The author’s team has been engaged in the clinical diagnosis and treatment of malignant tumors for a long time,and has conducted long-term observation and accumulation of the integrated treatment of liver cancer in TCM and Western medicine,extensively consulted ancient and modern literature,and repeatedly communicated with experts inside and outside the hospital.Through the analysis and improvement of the classic prescription Biejiajian Wan(鳖甲煎丸),the author gradually formulated the Bushen Huatan prescription(补肾化痰方),which is taken as the basic prescription.Combined with different clinical syndromes,the treatment method has achieved a certain effect,showing a certain clinical promotion value.Now several typical cases are reported and shared,and theoretical discussion is carried out to provide references for subsequent experimental research and even clinical research.