广西壮族自治区1304例肾活检病理资料流行病学特征

Epidemiological Characteristics of Pathological Data of 1304 Renal Biopsy Cases in Guangxi

目的 分析和总结广西地区1304例肾穿刺活检资料的流行病学特点及病理类型分布。方法 回顾性分析2012年—2021年在广西中医药大学第一附属医院行肾活检患者的肾脏病理资料,将其以5年为一个阶段分为两组,Ⅰ组(2012年—2016年)、Ⅱ组(2017年—2021年)以了解近年来此类患者病理类型的分布及变化特点。结果 1304例肾活检患者中,男女比例为1.19∶1。原发性肾小球疾病1082例(82.98%),其中常见的病理类型依次为膜性肾病、肾小球轻微病变、IgA肾病,占检出率分别为37.80%、28.56%、18.67%;继发性肾小球疾病204例(15.64%),以狼疮性肾炎最常见,其次是紫癜性肾小球肾炎和糖尿病肾病,检出率分别为64.22%、10.78%、10.78%。结论 地区10年间肾穿刺患者以原发性肾小球疾病最多见,其中膜性肾病是原发性肾小球疾病最常见的病理类型,狼疮性肾炎是最常见的继发性肾小球疾病。

Objective To analyze and summarize the epidemiological characteristics and pathologic distribution of 1304 renal biopsy cases in Guangxi.Methods The renal pathological data of patients who underwent renal biopsy in the First Affiliated Hospi-tal of Guangxi University of Traditional Chinese Medicine from 2012 to 2021 were retrospectively analyzed,and they were divided into two groups in 5 years,group I(2012-2016)and group II(2017-2021),to understand the distribution characteristics and variation of pathological types in recent years.Results Among 1304 renal biopsy patients,the male to female ratio was 1.19∶1.Primary glomerular disease in 1082 cases(82.98%),the common pathological types were membranous nephropathy,glomerular mild disease and IgA nephropathy,accounting for 37.80%,28.56%,18.67%of the total detection rate,respectively.Seconda-ry glomerular disease in 204 cases(15.64%),lupus nephritis was the most common,followed by purpura glomerulonephritis and diabetic nephritis,accounting for 64.22%,10.78%,10.78%of the total detection rate,respectively.Conclusions Primary glomerular disease is the most common in patients with renal puncture in this region for 10 years,of which membranous nephrop-athy is the most common pathological type of primary glomerular disease,and lupus nephritis is the most common secondary glo-merular disease.