基于“肠肾轴”理论探讨CKD相关菌群变化及其在一体化管理当中的意义

Exploring Changes in CKD-Related Flora and Their Significance in Integrated Management Based on"Gut-Renal Axis"

随着肠肾轴的理论提出,越来越多的研究发现来自CKD进展与肠道菌群改变之间的相互联系,这种相互联系深远地影响着CKD相关并发症的发生发展,是CKD一体化管理中的关键一环;文章着重从CKD相关菌群改变对CKD并发症及其在一体化管理中的意义来阐述,从肠肾轴角度出发,为探寻CKD相关治疗新方法的研究和试验奠定理论基础。

With the proposal of the gut-renal axis,more and more studies have found the correlation between the progression of chronic kidney disease(CKD)and the changes of intestinal flora,which has a profound impact on the occurrence and develop-ment of CKD-related complications and is a key link in the integrated management of CKD.This paper focuses on the CKD-related flora changes on the complications of CKD and its significance in the integrated management from the perspective of the gut-renal axis,in order to explore the new treatment of CKD-related research and experiment to lay a theoretical foundation.